ID A0A2I0MFE6_COLLI Unreviewed; 1389 AA.
AC A0A2I0MFE6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE SubName: Full=Sorbin and SH3 domain containing 1, transcript variant X7 {ECO:0000313|EMBL:PKK28413.1};
GN Name=SORBS1 {ECO:0000313|EMBL:PKK28413.1};
GN ORFNames=A306_00005099 {ECO:0000313|EMBL:PKK28413.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK28413.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK28413.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK28413.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK28413.1}.
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DR EMBL; AKCR02000016; PKK28413.1; -; Genomic_DNA.
DR RefSeq; XP_013227304.1; XM_013371850.1.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 458..561
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 802..861
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 876..937
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1328..1389
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 35..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1114..1129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1147
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1214..1239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1389 AA; 152738 MW; 9A93134F34F5FBA0 CRC64;
MDCVYLNAPK PYTQRVSPNA SARCYFSSPT PYGAIPSGKQ GLPAGHSPST GPKDEVHAGQ
PLLESRSLSD ASSLQRNPDR ADPSSKAGMN SSHETKADKK VTKLYVACLS NSTCSAASEN
STGTTHDPAA STSLGAEITQ APATDIVSSV TDTGKSLAAA APPPIPPRPY FYIVLSKDAV
SYDAGQPSWT QSSPPQAVRD RVLEAPSTAA TEDRMRKEPY LTQRRQPPYK AMGRSMDATA
TTTAQPGVIV VPLLQVNPDR QQEGSSSTPP PPLVPFGQGS VFPETVSSGS PLTFPTLDDF
IPPHLQRGFH HNQAPSASDT LPSVYPKLPF FSSPPSLVPP VTGALHRGSK PEITGVISHT
DSSPVLNEVP QPGTGTDYPT SFTSINKSSS AYPSTTIVNP TIVLLQHNRE QQKRLSSLAD
SVPDRLVSDK VDSAFIRDKP VLEALPSGKR AMEEKRSVVK SPQRMADTSV DDIGIPLRNT
DRSKDWYKTM FKQIHKINRD TPEENPYCPT YIFPELPEIQ QKTEEDNPYS PTYQFPASTP
SPISEDEDSD SYSPRYSYSE DSRTQLSVPR SKSEMDNIDS DKVVKRSATL PLPNRISSRK
SSPERTDWEP PDKKVDTRKY RAEPRSIYDY QPGKSSVLNN EKMNTAGGTP LETSTDRSSY
STYSPSYHAV KRESETALGD PAALENERQI YKSVLEGGDI PFQGLSGLKR PSSSASTRDS
DSSRHFTPVD YMETPEEIIR RRHDDKEKLL EDQRRLKREQ EEADIAARRH TGVIPTHHQF
ITNERFGDLL NVDDTAKRKS GSEMRPARAK FDFKAQTLKE LPLQKGDIVY IYKQIDQNWY
EGEHHGRVGI FPRSYIELLP PAEKAQPKKP SPLQVLEYGD AIAKFNFNGD TQVEMSFRKG
ERITLIRRVD ENWYEGRISG TNRQGIFPVT YVEVLKRPVV KNAIDYPDPP MSLSPNRSMT
ASPQSPSSEL LHTPTPPPLP FARRALSPEV QAVTSEWIAL TVGVSPSTTP AITPPLPPLP
EASLSPTDYL SPSAAASPSP SVSLHHSHLS GSSTPRSIKS PLPSYSSRPQ PSARSFYQAA
PQSEEKFVGS PSPSVTYSNS PRWAVGSPES VLAEQRDTAG SQAWLQKARE GSSSPERGTH
ADPKISVERC LKPSQLDMRV SPEKRPVGSS EDNQLCQELM AIVQGGKTEK RGMRKGDLGK
FQSGEKKPAD SKAFSSSAPL SSSALSSSTV TTQPPPRLTR RVNKPQPSHH SLRAGPDLTE
SEKSYVEAVC NEIINIAEKS VHYCSTVSQP LDSRHKVTSN DYKPSLIISQ QPQAQQQGAS
PDRSQTPRDI VSYQALYSYT PQNDDELELR DGDIVDVMEK CDDGWFVGTS RRTRQFGTFP
GNYVKLLYL
//
