ID A0A2I0MFX2_COLLI Unreviewed; 341 AA.
AC A0A2I0MFX2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
GN Name=CARNMT1 {ECO:0000313|EMBL:PKK28557.1};
GN ORFNames=A306_00007931 {ECO:0000313|EMBL:PKK28557.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK28557.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK28557.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK28557.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010086}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK28557.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKCR02000015; PKK28557.1; -; Genomic_DNA.
DR RefSeq; XP_005499843.1; XM_005499786.1.
DR AlphaFoldDB; A0A2I0MFX2; -.
DR STRING; 8932.A0A2I0MFX2; -.
DR GeneID; 102095931; -.
DR KEGG; clv:102095931; -.
DR InParanoid; A0A2I0MFX2; -.
DR OrthoDB; 167229at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0030735; F:carnosine N-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR012901; CARME.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR Pfam; PF07942; CARME; 1.
DR SMART; SM01296; N2227; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PKK28557.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PKK28557.1}.
SQ SEQUENCE 341 AA; 39772 MW; 7548B23B4233061C CRC64;
MTLNFLVFRT NMHERVNRTE RQFKSLPANQ QSLLPQFLPH LDKIRKCIDH NQQILQTIVN
DCARMFENKE YGEDGRGKIT PASTFDMDKL KSTLKQFVRD WSEEGKPERD SCYQPIISEI
VKNFPKERWD ISKVNILVPG AGLGRLAWEI AMLGYACQGN EWSLFMLFSS NFVLNRCSEI
NSCKLYPWIH QFSNNRRSAD QIRPIYFPDV DPHSLPSGSN FSMTAGDFQE IYSECNTWDC
IATCFFIDTA HNVIDYIDTI WKILKPGGVW INVGPLLYHF ENLGNELSIE LSYEDIKNVI
LQYGFHIEVE KESVLTTYTV NELSMMKYYY ECVLFVVRKP E
//
