ID A0A2I0MGS7_COLLI Unreviewed; 909 AA.
AC A0A2I0MGS7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=AF4/FMR2 family, member 1, transcript variant X2 {ECO:0000313|EMBL:PKK28868.1};
GN Name=AFF1 {ECO:0000313|EMBL:PKK28868.1};
GN ORFNames=A306_00006937 {ECO:0000313|EMBL:PKK28868.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK28868.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK28868.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK28868.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK28868.1}.
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DR EMBL; AKCR02000013; PKK28868.1; -; Genomic_DNA.
DR RefSeq; XP_005498559.1; XM_005498502.1.
DR AlphaFoldDB; A0A2I0MGS7; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 6.10.250.2670; -; 1.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF6; AF4_FMR2 FAMILY MEMBER 1; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 644..908
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 116..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..621
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 100167 MW; 91A2E7DF5D2706DE CRC64;
MNFAMAAQSS LYNEDRNLLR IREKERRNQE ALQERDIFPE KTPLFAEPYK TNKEDELSSR
IQNMLGNYEE VKELISNRSH QNLIGIPKSV APLIPQGKPD RPYFPEKTSR TLTSSFHRTT
RHPHMGPTVV APPPPSHSMH YQKAQSRTEP ASGLHAKSHS LSNGQSQGQE HNRGGQESHA
GFHHKRNDRR AVGEGHPNEL QASFLALSPL LPSLSSPVAP LSPLHSSQHI NSRSQNSSKS
HGPTHSQTKS SQDLVAGSQE KESRDSSAVN LTSTTQPSSQ TFPPPLPSKT SAMQQKPTAY
VRPMDGQDQA PVESPELKHL PEEYHGEPYE KISDLKVNAK AKLSKLKIPS EPIEQNFPSD
VHSIEDILKE MTHSWPPPLT AIHTPSTAEP SKFPFPTKES QHVGSVAQNQ KQYDAPSKTL
PSSQPRTSML QDDLQLSDSE ESGDDQVVEK PPSSFPPPSA LQSQPKSVAS AHSSSPESGS
TSDSDSSSDS ETESSSSESE ANDPPRAPAP EREMEKETDR KKTKSEKETK SLQSSANKDS
SKSKALKASF ETQKKDLLPP PLPPMSPAHP APKSTKTAQK RPRSESDELP TMDNTARNKS
NHKDPLFSKH KKVERNHAEL SKGIKGSAGD VTSPFSVPSL PNGTSKPRRP QLKLEKQHPM
EYYIEEAKRL KHKADAMTDK TGKAFQYLEA ALFFIEYGIA MESDGPAPKS GYSIFSDTID
LIKFIMTLIS FTDASASSHE KIFAVLCMRC QSILHMAMFR YKKDTAIKYS RILNDHFKSS
SRVTQAPSPC VARSTGMPSP LSPMPSPASS ASSQPGSNAS NCSGNSIGSS LTIPYTIPSI
TSSYVNITSY ILYAYDIWEQ ADALARKNKE FFAELSTATC TLALNSSMTE LVHYVRQGLQ
WLRLETNTP
//
