ID A0A2I0MI57_COLLI Unreviewed; 1202 AA.
AC A0A2I0MI57;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (Liprin), alpha 1, transcript variant X2 {ECO:0000313|EMBL:PKK29348.1};
GN Name=PPFIA1 {ECO:0000313|EMBL:PKK29348.1};
GN ORFNames=A306_00004767 {ECO:0000313|EMBL:PKK29348.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK29348.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK29348.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK29348.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK29348.1}.
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DR EMBL; AKCR02000011; PKK29348.1; -; Genomic_DNA.
DR RefSeq; XP_005511111.1; XM_005511054.2.
DR AlphaFoldDB; A0A2I0MI57; -.
DR GeneID; 102085521; -.
DR KEGG; clv:102085521; -.
DR CTD; 8500; -.
DR OrthoDB; 2906732at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF15; LIPRIN-ALPHA-1; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 878..944
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 970..1027
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1051..1120
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 97..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 252..443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 469..517
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 537..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..842
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1202 AA; 136188 MW; FF1D33A416AF147E CRC64;
MMCEVMPTIS EAEIPSGGNG GHGSGSPLQS DTDSHFEQLM VSMLEERDRL LETLRETQET
LALTQGKLHE VGHERDSLQR QLNTALPQEF AALTKELNVC REQLLEREEE IAELKAERNN
TRLLLEHLEC LVSRHERSLR MTVVKRQAQS PAGVSSEVEV LKALKSLFEH HKALDEKVRE
RLRVALERCS LLEEELGTTH KELMILKEQN NQKKTLPDGM LDINHEQENT PTTNGKRSSD
GSLCHDENLA KVLELQDVID KQNKEQTQMK ERLTALSSRV TELEEDLDTA RKDLIKSEEM
NTKLQRDVRE TMAQKEDMEE RITTLEKRYL AAQREATSVH DLNDKLENEI ATKDSMHRQS
EDKNRQLQER LELAEQKLQQ TLRKAETLPE VEAELAQRVA ALTKAEERHG NIEERLRQME
AQLEEKNQEL QRARQREKMN EEHNKRLSET VDKLLSESNE RLQLHLKERM AALEDKNSLI
REIEHAKKQI EELQHEKDQL VLNVEALRAE NDQVRLRATS LHHSRPDFRY PMAPSSVADS
HTDSYGTSSV LRRPQKGRLA ALRDEPSKVQ TLNEQDWERA QQASVLANVA QAFESDVDVS
DVEDDRETIF SSVDLLSPSG QADAQTLAMM LQEQLDAINK EIRLIQEEKE NTEQRAEEIE
SRVGSGSLDA HGRFRSMSSI PPPYASGSLA GSSPPGSGRS TPRRIPHSPA REVDRLGIMT
LSPASREEVR DDKTTIKCET SPPSSPRSLR LDRVQKGALH TVSHEDIRDI RNSTGSQDGQ
TSNPSSSNSS QDSLHKAPKK KGIKSSIGRL FGKKEKGRPG QTSKETLGQV GMGEADSSSQ
DALGLSKLGG QAEKNRKMQK KHELLEEARR QGLPFAQWDG PTVVVWLELW VGMPAWYVAA
CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE IMSLTSPSAP PTSRTTLAYG
DMNHEWIGNE WLPSLGLPQY RSYFMECLVD ARMLDHLTKK DLRGQLKMVD SFHRNSFQCG
IMCLRRLNYD RKELERKREE SQNEIKDVLV WSNERMIHWV VSIGLKEYAN NLIESGVHGA
LVALDESFDY NALALLLQIP TQNTQARAVL EKEFNNLLAM GTDRRLDEDD DKSFRRAPSW
RKKFRPKDIR GLAAGSAETL PANFRVTTSM SSPSMQPKKM QIDGSVSGTQ RLDSATVRTY
SC
//
