ID A0A2I0MJQ2_COLLI Unreviewed; 498 AA.
AC A0A2I0MJQ2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=TGF-beta activated kinase 1/MAP3K7 binding protein 1 {ECO:0000313|EMBL:PKK29907.1};
GN Name=TAB1 {ECO:0000313|EMBL:PKK29907.1};
GN ORFNames=A306_00004909 {ECO:0000313|EMBL:PKK29907.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK29907.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK29907.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK29907.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK29907.1}.
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DR EMBL; AKCR02000009; PKK29907.1; -; Genomic_DNA.
DR RefSeq; XP_013225030.1; XM_013369576.1.
DR AlphaFoldDB; A0A2I0MJQ2; -.
DR STRING; 8932.A0A2I0MJQ2; -.
DR InParanoid; A0A2I0MJQ2; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR PANTHER; PTHR13832:SF533; TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:PKK29907.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Transferase {ECO:0000313|EMBL:PKK29907.1}.
FT DOMAIN 24..361
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 410..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 54288 MW; 3CE1B38150418AEC CRC64;
MVVRHGHEQQ PSWTDDLPSC HLSGVGSAPN RSYSADGKGT EGHPLEDNWL KLRSENNCYL
YGVFNGYDGN RVTNFVGQRL SAELLLGQLR ADHSDADVRR VLLQAFDVVE RSFLESIDDA
LAEKASLQSQ LPEGVPHHQL PPQFQKIVER LKAVEQEISG GAMAIVAVVL NNKLYIANVG
TNRALLCKST VDGLQVTQLN VDHTTENEDE LFRFSQLGLD AGKIKQVGTI RGQESTRRIG
DYKVKYGYTD IELLSAAKSK PIIAEPEIHG GHSLDGVTGF LVLMSEGLYK ALEAAHGPGQ
ANQEIAAMIA TEFAKQTSLD AVAQAVVDRV KRIHCDTFAS GGERSKFCPR HEDMTLLVRN
FGYPLGEMSQ PTLTPTQGGR VYPVSVPYSS SQSTSKTSVT LSLVMPSQGQ MVNGAHSSST
LDEATPTLTN QSPTVTLQST NTHTQSSSSS SDGGLFRSRP THSLQPDEDG RVEPYVDFAE
FYRLWNMDHG EQGALTVS
//
