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Database: UniProt
Entry: A0A2I0MJT9_COLLI
LinkDB: A0A2I0MJT9_COLLI
Original site: A0A2I0MJT9_COLLI 
ID   A0A2I0MJT9_COLLI        Unreviewed;       455 AA.
AC   A0A2I0MJT9;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   31-JUL-2019, entry version 12.
DE   SubName: Full=Potassium channel, inwardly rectifying subfamily J, member 4, transcript variant X1 {ECO:0000313|EMBL:PKK29941.1};
GN   Name=KCNJ4 {ECO:0000313|EMBL:PKK29941.1};
GN   ORFNames=A306_00004925 {ECO:0000313|EMBL:PKK29941.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK29941.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK29941.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK29941.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock
RT   pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PKK29941.1}.
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DR   EMBL; AKCR02000009; PKK29941.1; -; Genomic_DNA.
DR   RefSeq; XP_005514754.1; XM_005514697.1.
DR   GeneID; 102096888; -.
DR   KEGG; clv:102096888; -.
DR   CTD; 3761; -.
DR   KO; K04998; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003273; K_chnl_inward-rec_Kir2.3.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR013673; K_chnl_inward-rec_Kir_N.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF53; PTHR11767:SF53; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   Pfam; PF08466; IRK_N; 1.
DR   PRINTS; PR01326; KIR23CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053872};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:PKK29941.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     88    114       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    167    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        6     52       IRK_N. {ECO:0000259|Pfam:PF08466}.
FT   DOMAIN       53    197       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      204    376       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION       28     47       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   455 AA;  51312 MW;  8793A2B473F0F035 CRC64;
     MIQRAMGSVR VNRYSVVSTE EDGHKVSALG SMNGHSRNGK GHAPRRKHRN RFVKKNGQCN
     VYFANLSNKS QRYMADIFTT CVDTRWRYML MIFSAAFLVS WLFFGFLFWC IAFFHGDLNA
     PAVAGGPSLL KPCIMHVNSF LGAFLFSVET QTTIGYGFRC VTEECPLAIM AVVVQSIVGC
     VIDSFMIGTI MAKMARPKKR AQTLLFSHHA VISVRDGKLC LMWRVGNLRR SHIVEAHVRA
     QLIKPYMTEE GEYLPLDQRD LNVGYDVGLD RIFLVSPIII VHEIDEESPL YGIGKEELET
     ENFEIVVILE GMVEATAMTT QARSSYLASE ILWGHRFEPV VFEEKNHYKV DYSRFHKTYE
     VAGTPCCSAR ELQESKMTIL PSPPPPSAFC YENELALVSQ DEDEDDDEVG VVLGGNTKEE
     GGVIQMMDFG SHLDLERIQA TLPLDTISYR RESAI
//
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