ID A0A2I0MKD0_COLLI Unreviewed; 206 AA.
AC A0A2I0MKD0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=FGF6 {ECO:0000313|EMBL:PKK30139.1};
GN ORFNames=A306_00004428 {ECO:0000313|EMBL:PKK30139.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK30139.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK30139.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK30139.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK30139.1}.
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DR EMBL; AKCR02000008; PKK30139.1; -; Genomic_DNA.
DR RefSeq; XP_005503096.1; XM_005503039.1.
DR AlphaFoldDB; A0A2I0MKD0; -.
DR STRING; 8932.A0A2I0MKD0; -.
DR GeneID; 102092640; -.
DR KEGG; clv:102092640; -.
DR CTD; 2251; -.
DR InParanoid; A0A2I0MKD0; -.
DR OrthoDB; 2883843at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF25; FIBROBLAST GROWTH FACTOR 6; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Mitogen {ECO:0000256|ARBA:ARBA00023246};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Signal {ECO:0000256|RuleBase:RU049442}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT CHAIN 37..206
FT /note="Fibroblast growth factor"
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT /id="PRO_5013985886"
SQ SEQUENCE 206 AA; 22855 MW; 5836FD129B486156 CRC64;
MATAQRLLIT MSCEASIHRT LPAFLLLGFL AGIASAHPVV SRTNGTLLER GWQSLLSRSI
AGMSGEKSDV NWESDYLLGI KRQRRLYCNV GIGFHLQILP DGRISGVHNE NQYSLFEIST
VERGVVSLFG VKSALFIAMN SKGRLYGTAV FQDECKFKET LLPNNYNAYE SNAYRGAYIA
LSKHGRVKRG NKVSPAMTVT HFLPRI
//
