ID A0A2I0MKK3_COLLI Unreviewed; 1073 AA.
AC A0A2I0MKK3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=ELKS/RAB6-interacting/CAST family member 1, transcript variant X1 {ECO:0000313|EMBL:PKK30212.1};
GN Name=ERC1 {ECO:0000313|EMBL:PKK30212.1};
GN ORFNames=A306_00004462 {ECO:0000313|EMBL:PKK30212.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK30212.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK30212.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK30212.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK30212.1}.
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DR EMBL; AKCR02000008; PKK30212.1; -; Genomic_DNA.
DR RefSeq; XP_005500363.1; XM_005500306.1.
DR AlphaFoldDB; A0A2I0MKK3; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0098793; C:presynapse; IEA:UniProt.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.2440; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR019323; ELKS/CAST.
DR InterPro; IPR037245; FIP-RBD_C_sf.
DR InterPro; IPR019018; Rab-bd_FIP-RBD.
DR PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR Pfam; PF10174; Cast; 2.
DR Pfam; PF09457; RBD-FIP; 1.
DR SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51511; FIP_RBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 1003..1065
FT /note="FIP-RBD"
FT /evidence="ECO:0000259|PROSITE:PS51511"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 151..178
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 215..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 31..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1073 AA; 123297 MW; FAE09F42C3515162 CRC64;
MYGSARSVGK VEPSNQSPGR SPRLPRSPRL GHRRTNSTGG SSGSSTAGGS GKTLSMENIQ
SLNAAYATSG PMYLSDHENV GADTPKSTMT LGRSGGRLPY GVRMTAMGSS PNIASSGVAS
DTIAFGEHHL PPVSMASTVP HSLRQARDNT IMDLQTQLKE VLRENDLLRK DVEVKESKLS
SSMNSIKTFW SPELKKERAL RKDEASKITI WKEQYRVLQE ENQHMQMTIQ ALQDELRIQR
DLNQLFQQDS STRTSEPFVA ELTEENFQRL HAEHERQAKE LFLLRKTLEE MELRIETQKQ
TLNARDESIK KLLEMLQSKG LSAKATEEDH ERTRRLAEAE MHMHHLESLL EQKEKENNML
REEIHRRFEN APDTAKTKAL QTVIEMKDSK ISSMERGLRD LEEEIQMLKS NGALSTEERE
EEMKQMEVYR SHSKFMKNKV EQLKEELSAK EAQGEDLKKR VAGLQAEIGQ VKQELSRKDT
ELLALQTKLE TLTNQFSDSK QHIEVLKESL TAKEQRAAIL QTEVDALRLR LEEKETMLNK
KTKQIQEMAE EKGTQAGEIH DLKDMLEVKE RKVNVLQKKI ENLQEQLRDK EKQMSSLKDR
VKSLQADTTN TDTALTTLEE ALAEKERTIE RLKEQRDRDE REKQEEIDNY KKDIKDLKEK
VSILQGDLTE KETSLLDLKE HASSLASSGL KKDSRLKTLE IALEQKKEEC LKMETQLKKA
HEATLEARAS PELSDRMQQL EREVTRYREE SSKAQAEVDR LLEILKEMEN EKNDKDKKIA
ELERQVKDQN KKVANLKHKE QVEKKKSAQM LEEARRREDN LNDSSQQLQV EELMMAMEKV
KQELESMKAK LSSTQQSLAE KETHLTNLRA ERRKHLEEVL EMKQEALLAA ISEKDANIAL
LELSSSKKKT QDEVAALKRE KDRLVQQLKQ QTQNRMKLMA DNYEDDHLKS SSHSNQTNHK
PSPDQIIQPL LELDQNRSKL KLYIGHLTAL CHDRDPLILR GLTPPASYHL DDDRAAWEKE
LQKMTQEQLH EELEKGEKES AELQEFANAI LQQIADHCPD ILEQVVNALE ESS
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