ID   A0A2I0MM98_COLLI        Unreviewed;       913 AA.
AC   A0A2I0MM98;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Exocyst complex component 1, transcript variant X3 {ECO:0000313|EMBL:PKK30809.1};
GN   Name=EXOC1 {ECO:0000313|EMBL:PKK30809.1};
GN   ORFNames=A306_00003535 {ECO:0000313|EMBL:PKK30809.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK30809.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK30809.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK30809.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- SIMILARITY: Belongs to the SEC3 family.
CC       {ECO:0000256|ARBA:ARBA00006518}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKK30809.1}.
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DR   EMBL; AKCR02000006; PKK30809.1; -; Genomic_DNA.
DR   RefSeq; XP_013222079.1; XM_013366625.1.
DR   AlphaFoldDB; A0A2I0MM98; -.
DR   GeneID; 102086149; -.
DR   CTD; 55763; -.
DR   OrthoDB; 6810at2759; -.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0000145; C:exocyst; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   CDD; cd14683; PH-EXOC1; 1.
DR   Gene3D; 2.30.29.90; -; 1.
DR   InterPro; IPR028258; Sec3-PIP2_bind.
DR   InterPro; IPR048628; Sec3_C.
DR   InterPro; IPR019160; Sec3_CC.
DR   PANTHER; PTHR16092:SF33; EXOCYST COMPLEX COMPONENT 1; 1.
DR   PANTHER; PTHR16092; SEC3/SYNTAXIN-RELATED; 1.
DR   Pfam; PF15277; Sec3-PIP2_bind; 1.
DR   Pfam; PF20654; Sec3_C-term; 1.
DR   Pfam; PF09763; Sec3_CC; 1.
DR   SMART; SM01313; Sec3-PIP2_bind; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          31..122
FT                   /note="Exocyst complex component Sec3 PIP2-binding N-
FT                   terminal"
FT                   /evidence="ECO:0000259|SMART:SM01313"
FT   REGION          460..513
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          565..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          207..255
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        460..474
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..513
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   913 AA;  104168 MW;  13CDB7BA0C605EA0 CRC64;
     MTAIKHALQR DIFTPNDERL LSIVNVCKAG KKKRNCFLCA TVTTERPVQV NVVKVKKSDK
     GDFYKRQTAW GLRDLAVVDA KDAVKENPEF DLHFDKVYKW VASSTVEKNT FISCIWKLNQ
     RYLRKKIDFI NVSSQLLEES VPSGENQSVT GGDEESVDEY QELNAREEQD IEIMMEGCEY
     AISNAEAFAE KLSRELQVLD GANIQSIMAS EKQVNILMKL LDEALKEVDQ IELKLSSYEE
     MLQSVKEQMD QISESNHLIH LSNTNNVKLL SEIEFLVNHM DLAKGHIKAL QEGDLTSSRG
     IEACTNAADA LLQCMNVALR PGHDMLQAVK QQQQRFGDLR EQFARRLASH LNSVFVHQFN
     QNFLQLCNRP YSLSVAGHDQ SSTLAQHSAE LTLPNHHPFH RDLLRYAKLM EWLKNTDYGK
     YEGLTKNYMD YLSRLYEREI KDFFEVAKIK MTGTTREGKK FATLPRKESA VKQETESLHG
     SSGKLTGSTS SLNKLSVQSS GSRRSQSSSL LDMGNMSASD LDVADRTKFD KIFEQVLSEL
     EPLCLAEQDF ISKFFKLQQH QSISGTTTNE AEEMDGGTLS RSYTSGVPQT ISSEKDMIRQ
     MMTKIFRCIE PELNNLIALG DKIDSFNSLY MLVKMSHHVW TAQNVDPASF LSTTLGNVLV
     TVKRNFDKCI SNQMKQMDEV KISKKSKVGI LPFVAEFEEF AALAESIFKN AERRGDLDKA
     YTKLIRAVFV SVEKVANESQ KTPRDVVMME NFHHIFATLS RLKISCLEAE KKEAKQKYTD
     HLQSYVIYSL GQPLEKLNHF FEGVEARVAQ GIREEEVSYQ LAFNKQELRK VIKEYPGKEV
     KKGLDNLYKK VDKHLCEEEN LLQVVWHSMQ DEFIRQYKHF EGLIARCYPG SGITMEFTIQ
     DILDYCSSIA QSH
//