ID A0A2I0MMD2_COLLI Unreviewed; 767 AA.
AC A0A2I0MMD2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Adducin 1 (Alpha), transcript variant X1 {ECO:0000313|EMBL:PKK30839.1};
GN Name=ADD1 {ECO:0000313|EMBL:PKK30839.1};
GN ORFNames=A306_00003364 {ECO:0000313|EMBL:PKK30839.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK30839.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK30839.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK30839.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}.
CC -!- SIMILARITY: Belongs to the aldolase class II family. Adducin subfamily.
CC {ECO:0000256|ARBA:ARBA00006274}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK30839.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKCR02000006; PKK30839.1; -; Genomic_DNA.
DR RefSeq; XP_005498508.1; XM_005498451.1.
DR AlphaFoldDB; A0A2I0MMD2; -.
DR STRING; 8932.A0A2I0MMD2; -.
DR GeneID; 102092515; -.
DR KEGG; clv:102092515; -.
DR CTD; 118; -.
DR InParanoid; A0A2I0MMD2; -.
DR OrthoDB; 45123at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00398; Aldolase_II; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR001303; Aldolase_II/adducin_N.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR PANTHER; PTHR10672; ADDUCIN; 1.
DR PANTHER; PTHR10672:SF4; ALPHA-ADDUCIN; 1.
DR Pfam; PF00596; Aldolase_II; 1.
DR SMART; SM01007; Aldolase_II; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 147..329
FT /note="Class II aldolase/adducin N-terminal"
FT /evidence="ECO:0000259|SMART:SM01007"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..662
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 84595 MW; 467F1AFE46B555C3 CRC64;
MNGDSGVGVV TSPPPTTAPH KERYFDRVDE NNPDYLRERN MAPDLRQDFN MMEQKKRVSM
ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT NVPNVYPAAP QGGMAALNMS
LGMVTPVNDL RGSDSIAYEK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT ARVNSEQEHF
LIVPFGLLYS EVTASSLVKV NLQGDVVDRG STNLGVNQAG FTLHSAIYAA RPDVKCIVHI
HTPAGAAVSA MKCGLLPISP EALSLGEVAY HDYHGILVDD EEKVVIQKNL GPKSKVLILR
NHGLVSVGET VEEAFYYIHN LVLACEIQVR TLASAGGPDN LVLLDPGKYK AKSRSPESPA
GEGTVSHPKW QIGEQEFEAL MRMLDNLGYR TGYPYRCPAL REKSKKYSDV EIPASVTGYS
FTSDGESGTC SPLRHSFQKQ QREKTRWLNS GRGDDASEEG QNGSSPKSKT KVWTNITHDH
VKPLLQSLSS GVCVPSCITN CLWTKEDGHR TATSAVPNLF VPLNTNPKEV QEMRNKIREQ
NLQDIKTAGP QSQVLSGVVV DRSLVQGELV TASKAIIEKE YQPKVIVSTT GPNPFNKLTD
RELEEYRKEV ERKQKGPEEP SEDGRQQKER SPPDHTSART PPSTPIKIEE ERQQDQTYKD
DSDAATFKQT LPDLTPDEPS EALGFPPLGK EEGRCDEDVP KSQTESPAVE NKEPQPQPAE
EAVTPPAEEG PAADAGSDES PGKSPSKKKK KFRTPSFLKK SKKKSDS
//
