ID A0A2I0MMP2_COLLI Unreviewed; 1012 AA.
AC A0A2I0MMP2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Sorbin and SH3 domain containing 2, transcript variant X21 {ECO:0000313|EMBL:PKK30946.1};
GN Name=SORBS2 {ECO:0000313|EMBL:PKK30946.1};
GN ORFNames=A306_00003570 {ECO:0000313|EMBL:PKK30946.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK30946.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK30946.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK30946.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK30946.1}.
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DR EMBL; AKCR02000006; PKK30946.1; -; Genomic_DNA.
DR RefSeq; XP_013227372.1; XM_013371918.1.
DR AlphaFoldDB; A0A2I0MMP2; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR CDD; cd11920; SH3_Sorbs2_1; 1.
DR CDD; cd11923; SH3_Sorbs2_2; 1.
DR CDD; cd11917; SH3_Sorbs2_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 504..565
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 774..833
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 849..910
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 953..1012
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..619
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..761
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 111140 MW; EC782A998FCB0759 CRC64;
MNTGSDSQSS DSAWRSYNDG SRETLNGDAS SSSLTAKGFR SVRPNLQDKK SPSQAPLPPP
RKESFRKARV TNNKNGINLQ TVTSSPAKHL PTDSAYYTNE ISVQETMSSQ LTNTSVSYAQ
KITKPLTSIS SAGTSTVAGI STTLHQGQRQ QSPKRRVSTL KLTRTRDAAS SIPCNTQQQL
KPVEVPVSPQ RPVSPACNPV PEIHTASLSI QIAPIPDNKA EPEIQEHPPS ISPDTSKMSS
QDLRQKSTVL PSSQAAECHV LGNQKVTAPV MEVNASQTHR QTATEASPLP LPPPVVPVNR
ASFSPDSGTH LVPYSLPALD DFLPSRFYKT PALSQFSYKC PYLASESIIH RNETASVSTD
SAMSECSSRT VSESSTAILD ELQTCSYDTT DCSETPSPTL SQMSAVSDGT TLTNTAATSH
AQITVNGNSG TAASPVSHFQ RPFSPSSVYP PPASLNSNIV IMQHGRMMES TETYSEHVQT
VGSTTTTSTI PICRSSEEEK KITVIKAPHY AGIGPVDESG IPTAIRTTVD RPKDWYKTMF
KQIHMVHKPD DATDMYNTAY AYSTGSYSPS FSAQAHPAAK TQTYRPLSKS ASDSSADAFK
VSSPLPPPHV PPPVPPHRMR GRSTPEKNDW DPPDRKVDTR KFRSEPRSIF EYEPGKSSIL
EHERPTSLYY RYSTEKGLDR PSSSASTASD YRKRRKSEPA VSHQRVHSDQ NANRPGLGRT
DLQGPCTTLR KPLTSSSPSS PSRAKDQESP GSYSSAFTDV GRSTPRDRRG TTDKEKLPAR
AVYDFKAQTS KELSFKKGDT VYILRKIDQN WYEGEHHGRV GIFPISYVEK LSPPEKAQPA
RPPPPAQIGE IGEAIAKYNF SADTNVELSL RKGDRVILLK RVDQNWYEGK IPGTNRQGIF
PVSYVEVIKK NASKSVDDYP DPPIPQSYSS DRIHHLSSTK PQRPVLAHEN IQSGGEPFQA
LYNYTPRNED ELELREGDVI DVMEKCDDGW FVGTSRRTKF FGTFPGNYVK RL
//
