ID A0A2I0MMY6_COLLI Unreviewed; 945 AA.
AC A0A2I0MMY6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Zinc finger, FYVE domain containing 28 {ECO:0000313|EMBL:PKK31044.1};
DE Flags: Fragment;
GN Name=ZFYVE28 {ECO:0000313|EMBL:PKK31044.1};
GN ORFNames=A306_00003358 {ECO:0000313|EMBL:PKK31044.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK31044.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK31044.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK31044.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the lst-2 family.
CC {ECO:0000256|ARBA:ARBA00008755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK31044.1}.
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DR EMBL; AKCR02000006; PKK31044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0MMY6; -.
DR STRING; 8932.A0A2I0MMY6; -.
DR InParanoid; A0A2I0MMY6; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15731; FYVE_LST2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043269; FYVE_LST2.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46465; LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG; 1.
DR PANTHER; PTHR46465:SF2; LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 875..931
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 343..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..704
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PKK31044.1"
SQ SEQUENCE 945 AA; 105166 MW; F6835AB539304AE6 CRC64;
DPQLLAQFYY ADEELNQVAA ELDSLDGRKD PQRCTLLVNQ FRSCQDNVLN IINQIMDECI
PHERANRDFC VKFPEEIRHD NLAGQLWFGA ECLAAGSIIM NREIESMAMR PLAKDLTRSL
EEVRNIIRDQ ALRDLNLYTE KMKDSLKHFD VLFAEFELSY VSAMVPVKSP KEYYVQQEVI
VLFCETVERA LRLGYLTQDM IDDYEPALMF TIPRLAIVCG LVVYSEGPLN LDHKPEDMSE
LFRPFHTLLR KIRDLLQTLT EDELHTLERN LCISQDVDFP VRADPEVPSV ITPGITATLP
AKQLSGKAEN TEAELACSMQ YDEQELEQLN RMVHRVGDEM SSLLSPPSIC QSPAHRPSVR
NTSSTEASPT RHHLDNLTDE EDRVFFMDDL DGAGEALAGL DSVGDTFAWV NNPCHDSKQN
LQYRDALLYE NGHQAEETLL LKDAESDLSN NNNIEDSKQM SGISVQNSCS CLEGPDSQLY
LNGWDAYADD AEMAEVIAHR TGGMKISATV IFNPKSPSSS ESPVTTPEAA ISCVPGSANP
LPNEEDESHK LSIAATNCLI NSCVCCGSCE DSREDSVKGL KTKHSAGGVV NASYTLVKSK
EMDRVDNLDD SVPAQETLRP ETSALLAERD FGREEQKLPV SSKCLAHSSG SQVGAENDSQ
GEAESITNQQ KKWEKRKQLC EKKQDNNEDA HSERTAKEDV KSRSSSSSQD GLRDSPLSSI
SSSDYESVSV TTCSVSSIYA LSSLMTSSSS SDDIDEEEIQ LALQAAKIAT REKIRSRFHG
SNDLIHRLFV CISGVADQLQ TNYASDLRSI LKTLFEVMAT KPETEDKEKQ KKANQGLRNA
ALEDCALCQE SISSSELAAK ARDGDFEDPP DWVPDEVCSY CTACKAPFTV IRRKHHCRSC
GKIFCSRCSS HSAPLPRYGQ MKPVRVCTHC YMFHVTPFYS DKAGI
//
