ID A0A2I0MNB6_COLLI Unreviewed; 635 AA.
AC A0A2I0MNB6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit {ECO:0000313|EMBL:PKK31169.1};
DE Flags: Fragment;
GN Name=BRF1 {ECO:0000313|EMBL:PKK31169.1};
GN ORFNames=A306_00002310 {ECO:0000313|EMBL:PKK31169.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK31169.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK31169.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK31169.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK31169.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKCR02000005; PKK31169.1; -; Genomic_DNA.
DR RefSeq; XP_005506435.2; XM_005506378.2.
DR AlphaFoldDB; A0A2I0MNB6; -.
DR STRING; 8932.A0A2I0MNB6; -.
DR GeneID; 102092953; -.
DR KEGG; clv:102092953; -.
DR CTD; 2972; -.
DR InParanoid; A0A2I0MNB6; -.
DR OrthoDB; 5483352at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20553; CYCLIN_TFIIIB90_rpt1; 1.
DR CDD; cd20554; CYCLIN_TFIIIB90_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR Gene3D; 1.20.5.650; Single helix bin; 1.
DR InterPro; IPR011665; BRF1_TBP-bd_dom.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR PANTHER; PTHR11618:SF4; TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF07741; BRF1; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Initiation factor {ECO:0000313|EMBL:PKK31169.1};
KW Protein biosynthesis {ECO:0000313|EMBL:PKK31169.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 43..124
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 137..221
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 387..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 259..286
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 449..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PKK31169.1"
SQ SEQUENCE 635 AA; 70767 MW; CDC60A1295EEC476 CRC64;
GGSSAVGQFV SLDGAGKTPT LGGGFHANLG KESRAQTLQN GKRQIHHLGN QLQLNQHCLD
TAFNFFKMAV SKHLTRGRKM THVIAACLYL VCRTEGTPHM LLDLSDLLQV NVYVLGKTFL
LLARELCINA PAIDPCLYIP RFAHMLEFGD KNHEVSMTAL RLLQRMKRDW MHTGRRPSGL
CGAALLVAAR MHDFRRTVKE VIRVVKVCES TLRKRLTEFE DTPTSQLTID EFMKIDLEEE
CDPPSFTAGQ RKLKIQQLEK ALSKKLEDFE GEISSYQDEI EIELENSRPK AKGVFANFTK
DDSIEDNTSS VLGEEEAEDE ELEAAANHLN KDFCNELHEK DGVKRNEDGG CKNGNQAFVR
PPALESLLGP LPTAASLGIT ESIKECISTK DQEPDENTGD GELDLSGIDD SEIDRYILNE
TEAQIKAELW MKENADYLKE QKEKEARIAK EKELGIYKEH KPKKSAKKRE PIQASTAGEA
IEKMLEQKKI SSKINYNVLR DLNSKGSNTP KKEDDSTDDS TNTKKLSRRK SIASRSIANP
VNSVGKRLRP LISTQLAKKA KKAATEEMTF PNAQAEAPDV EKTAAVLVES GPVAYNADEE
VEEEEIEEDD DHCMSALQLM GGNDYGCDME DDDGY
//
