ID A0A2I0MPW9_COLLI Unreviewed; 455 AA.
AC A0A2I0MPW9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Tetratricopeptide repeat domain 8, transcript variant X1 {ECO:0000313|EMBL:PKK31697.1};
GN Name=TTC8 {ECO:0000313|EMBL:PKK31697.1};
GN ORFNames=A306_00002188 {ECO:0000313|EMBL:PKK31697.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK31697.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK31697.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK31697.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK31697.1}.
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DR EMBL; AKCR02000005; PKK31697.1; -; Genomic_DNA.
DR RefSeq; XP_013223658.1; XM_013368204.1.
DR AlphaFoldDB; A0A2I0MPW9; -.
DR STRING; 8932.A0A2I0MPW9; -.
DR GeneID; 102090175; -.
DR KEGG; clv:102090175; -.
DR CTD; 123016; -.
DR InParanoid; A0A2I0MPW9; -.
DR OrthoDB; 1328318at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:1905515; P:non-motile cilium assembly; IEA:InterPro.
DR CDD; cd21341; TTC8_N; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR028796; BBS8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44177; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR PANTHER; PTHR44177:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR Pfam; PF13181; TPR_8; 3.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 371..404
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 32..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 51230 MW; EAFED4EE6821F37D CRC64;
MVYVDEIDMD QEGIAEMMLD ENAIAQVARP GTSLKLPGTS QGGGPSPAVR PVTQSGRPIT
GFVRPGTQGG RPSTMEQAIK TPRTSLTARP ITSASGRYGR LGTASMLTNP DGPFINLSRL
NLAKYAQKPK LAKALFEYIF YHENDVKNAL DLAALATEHA QFKDWWWKVQ IGKCYYRLGL
YREAEKQFKS ALKQQDMVDT ILYLAKVYLR LDQPVTALNL FKQGLDRFPG EVTLICGIAR
IYEEMNNIST AAEYYKDVLK QDNTHVEAIA CIGSNHFYSD QPEIALRFYR RLLQMGVHNC
QLFNNLGLCC FYAQQYDMTL SSFERALFLA ENEEETADVW YNLGHVAVGI GDLNLAYQCF
KLTLINNNNY AEAYNNLAVL EMRKGHIEQA RAFLQTASSL APHMYEPHFN FAILSEKVGD
LQRSYAAAKK SEEAFPGHVD TQQLIKELKQ HFAVL
//
