ID A0A2I0MR22_COLLI Unreviewed; 521 AA.
AC A0A2I0MR22;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Abl-interactor 1, transcript variant X4 {ECO:0000313|EMBL:PKK32137.1};
DE Flags: Fragment;
GN Name=ABI1 {ECO:0000313|EMBL:PKK32137.1};
GN ORFNames=A306_00002497 {ECO:0000313|EMBL:PKK32137.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK32137.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK32137.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK32137.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Cell projection, filopodium
CC {ECO:0000256|ARBA:ARBA00004486}. Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}.
CC -!- SIMILARITY: Belongs to the ABI family. {ECO:0000256|ARBA:ARBA00010020}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK32137.1}.
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DR EMBL; AKCR02000004; PKK32137.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0MR22; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR CDD; cd11971; SH3_Abi1; 1.
DR Gene3D; 6.10.140.1620; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR028457; ABI.
DR InterPro; IPR035725; Abi1_SH3.
DR InterPro; IPR012849; Abl-interactor_HHR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR10460:SF7; ABI GENE FAMILY MEMBER 3; 1.
DR PANTHER; PTHR10460; ABL INTERACTOR FAMILY MEMBER; 1.
DR Pfam; PF07815; Abi_HHR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 87..149
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 459..518
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 201..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..340
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..434
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PKK32137.1"
SQ SEQUENCE 521 AA; 56547 MW; C7E0E8663EA87C37 CRC64;
WVGKASAHES EARRNPTIPG GLRARRCRCL FNARGSDAEG WKMAELQMLL EEEIPSGKRA
LLESYQNLTR VADYCENNYI QAPDKRKALE ETKAYTTQSL ASVAYQINAL ANNVLQLLDI
QASQLRRMES SINHISQTVD IHKEKVARRE IGILTTNKNT SRTHKIIAPA NMERPVRYIR
KPIDYTVLDD VGHGVKWLKA KHGNNQPART GTLSRTNPPT QKPPSPPMSG RGTLGRNTPY
KTLEPVKPPT VPNDYMTSPA RLGSQHSPGR TASLNQRPRT HSGSSGGSGS RENSGSSSIG
IPIAVPTPSP PTVGPAHISV PPPPGAPPAP PLPPPLPLGS LIAAPGSAPG SQYGTMTRQI
SRHNSTTSST SSGGYRRNPS VTAPFSAQPH VNGGPLYSQN SIADSPTPPP PPPPDEMPMF
DDSPPPPPPP PVDYEDEEAA VVQYSDPYAD GDPAWAPKNY IEKVVAIYDY TKDKDDELSF
MEGAIIYVIK KNDDGWYEGV CNRVTGLFPG NYVESIMHYA D
//
