ID A0A2I0MT62_COLLI Unreviewed; 803 AA.
AC A0A2I0MT62;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=SLIT and NTRK-like family, member 5 {ECO:0000313|EMBL:PKK32867.1};
GN Name=SLITRK5 {ECO:0000313|EMBL:PKK32867.1};
GN ORFNames=A306_00003145 {ECO:0000313|EMBL:PKK32867.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK32867.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK32867.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK32867.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the SLITRK family.
CC {ECO:0000256|ARBA:ARBA00010439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK32867.1}.
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DR EMBL; AKCR02000003; PKK32867.1; -; Genomic_DNA.
DR RefSeq; XP_005506049.1; XM_005505992.1.
DR AlphaFoldDB; A0A2I0MT62; -.
DR STRING; 8932.A0A2I0MT62; -.
DR InParanoid; A0A2I0MT62; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007409; P:axonogenesis; IEA:InterPro.
DR GO; GO:1905606; P:regulation of presynapse assembly; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR043326; Slitrk.
DR PANTHER; PTHR45773; SLIT AND NTRK-LIKE PROTEIN 4-RELATED; 1.
DR PANTHER; PTHR45773:SF5; SLIT AND NTRK-LIKE PROTEIN 5; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00082; LRRCT; 2.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 235..285
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT DOMAIN 563..613
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 322..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 803 AA; 89998 MW; 810A6F7172EAFEE9 CRC64;
MYACCSTVTL EQDLNKKMHI WMLQTIVFAL TSLVLSWAES IEYYGEICDN ACPCEEKDGI
LTVSCENRGI ISLFEISPPR FPVYHLLLSG NLLNRLYPNQ FVNYTGASIL HLGSNDIQDI
ETGAFHGLKG LRRLHLNNNK LELLRDDTFL GLESLEYLQV DYNYISVIEP NAFSKLHLLQ
VLILNDNLLS SLPNNLFRFV PLTHLDLRGN RLKLLPYVGL LQHMDKVVEL QLEENPWNCS
CELIALKDWL DSISYSALVG DVVCETPFRL HGRDLDEVSK QELCPRRLIS DYEMRPQTPL
STTGYFHTTP ASVNSVATSS SAVYKSPLKP PKGTRQPNKT RVRPTSRLPS KDLGYSNYGP
SIAYQTKSPV PLECPTACTC NLQISDLGLN VNCQERKIES ISELQPKPYN PKKMYLTENY
IALVRRADFV DATGLDLLHL GNNRISVIQD RAFGDLTNLR RLYLNGNRIE RLSPELFYGL
QSLQYLFLQY NVIREIEAGT FEPVPNLQLL FLNNNLLRSL PGNIFSGLSL YRLSLRSNHF
SYLPVSGVLD QLKSLLQIDL HENPWDCTCD VVGMKLWLEQ LNTGVLVDQV ICESPKKFSQ
NDMRAVRVEL LCPDYSDIVV STPTPSPGQL PARTTPSSST VRLNGTAAAG GSAPAGGAGG
GSSSVPLSVL ILSLLLVFIM SVFVAREELL SPVQDADRFY RGILEPDKHS SSSTLGTPGS
TLPDYSKLPA AYTYSPNYDL RRAHQYLHPG PGDGRLRETV LYSPPSTVFV EPNRNEYLEL
KAKLNAEPDY LEVLEKQTTF SQF
//
