ID A0A2I0MU66_COLLI Unreviewed; 1195 AA.
AC A0A2I0MU66;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=SAM and SH3 domain containing 1, transcript variant X1 {ECO:0000313|EMBL:PKK33220.1};
GN Name=SASH1 {ECO:0000313|EMBL:PKK33220.1};
GN ORFNames=A306_00000644 {ECO:0000313|EMBL:PKK33220.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK33220.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK33220.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK33220.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK33220.1}.
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DR EMBL; AKCR02000002; PKK33220.1; -; Genomic_DNA.
DR RefSeq; XP_005507689.1; XM_005507632.2.
DR AlphaFoldDB; A0A2I0MU66; -.
DR STRING; 8932.A0A2I0MU66; -.
DR InParanoid; A0A2I0MU66; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR CDD; cd09559; SAM_SASH1_repeat1; 1.
DR CDD; cd09492; SAM_SASH1_repeat2; 1.
DR CDD; cd11967; SH3_SASH1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037627; SASH1_SAM_repeat1.
DR InterPro; IPR037630; SASH1_SAM_repeat2.
DR InterPro; IPR035720; SASH1_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR021090; SPIDER.
DR PANTHER; PTHR12301:SF3; SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12301; SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF12485; SLY; 1.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 505..566
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 584..648
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1130..1190
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 40..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..504
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1195 AA; 132096 MW; ABC4DC247D7F5471 CRC64;
MGILDGSLGN IDDLAQQYAD YYNTCFTDVC ERMEELRKRR VSQDLDTDKP DASPTSLQLR
SQIEESLGLS STASTPDTER KLSIHKSSSE ESSVGKADWK KKNKFFWQNF RKNQKGLMRQ
TSKGEDVGYV ASEITMSDEE RIQLMMMVKE KMITIEEALA RLKEYEAQHR QSSTVDTTEW
PDGSYSAFDG SSNCNSREQS DDETEESVKF KRLHKLVNST RRVRKKLIRV EEMKKPSTEG
VEEHSLDNSP ILDDRSALYS GVHKKQFYFD GSCEKQPEDD SDSLTTSPSS SSLDTWGANR
KLVKTLSKTD SRGLIKPPKK LGTFFSYPEE EKTQKVCRSL TDGEMKKSLG SLSHGRTCSF
GGFDLTNRSL HIGNSSDQMG KEGDFVYKEV IKSPSASRIS LGKKVKSVKE TMKKRMSKKY
SSSLSEQESS PGVMPGSPQS PPPDTDSLDK PKLKAGGSVE SLRSSLSGQS SMSGQTVSTT
DSSTSNRESV KSEDGDDEEP PYRGPFCGRA RVHTDFTPSP YDTDSLKLKK GDIIDIISKP
PMGTWMGLLN NKVGTFKFIY VDVLNEEEEK PKRPTRRRRK SRPPQPKSVE DLLDRINLKE
HMPTFLFNGY EDLDTFKLLE EEDLDELNIR DPEHRAVLLT AVELLQEYDS NSDQSGSQEK
LLIEGQSLTG CSPRDSGCYE SSENLENGKT RRNCLLPSKS ASEHSFKDFS RNQLSNYPTL
PLTKSIETLQ QGGNESRLSC AHRALKSSVN PPGVTGLKKN RRSLPVAVCR SYETLDGPQG
VDTWPRSHSL DDLQGESNTN LQGTSKKVGS FPQDSLDIAK KATSSAPQPH GGGCVVDDLM
PKQGKGAASS QKGRAKELDC SVMETAGGKP ARFPLKHCEA QPALVTHLAT RTPLEIQNKG
FHDLARADYA AVLKGGLEAE QKGTNEARMQ PKNPSQPPPV PAKKCRERLS NGLYHPPTTA
SGNHSSLEAP CLPVKKTSSC TPVDCHGAPV HRTSSEQEPS TPPSPLPPWL SELPETASVQ
QHVIKLGPAS ARKVSCSRGL DLEMVIENKL QSEDIDLTEE PYSDKHGRCG IPEALVQRYS
EDLDQPVKDV ATNMDQIRVK QLRKQHRMAI PSGGLTEICR KPVSPGLITS VSDWLISIGL
PMYSSLLTEA GFNTLSKVPS LSQTCLQEAG ITEERHISKL LAAARLFKPL DPEAI
//
