ID A0A2I0MVE9_COLLI Unreviewed; 356 AA.
AC A0A2I0MVE9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Nuclear receptor subfamily 2 group E member 1 {ECO:0000256|ARBA:ARBA00040364};
DE AltName: Full=Nuclear receptor TLX {ECO:0000256|ARBA:ARBA00042524};
DE AltName: Full=Protein tailless homolog {ECO:0000256|ARBA:ARBA00041813};
GN Name=NR2E1 {ECO:0000313|EMBL:PKK33658.1};
GN ORFNames=A306_00000856 {ECO:0000313|EMBL:PKK33658.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK33658.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK33658.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK33658.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR2
CC subfamily. {ECO:0000256|ARBA:ARBA00006421}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK33658.1}.
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DR EMBL; AKCR02000002; PKK33658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0MVE9; -.
DR STRING; 8932.A0A2I0MVE9; -.
DR InParanoid; A0A2I0MVE9; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd06950; NR_LBD_Tlx_PNR_like; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24083:SF98; NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR SMART; SM00430; HOLI; 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:PKK33658.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 126..354
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 356 AA; 38622 MW; 19F11452846B6A57 CRC64;
MGFTPVMGAR DFSSGASGGI GPMFANREIR EGSPAKQRGV PSVGPHGDSL ASALCPAAVQ
HERGPRTSTI RKQVALYFRG HKEESGGAPH FPAAALPAPA FFTAVSQLEP HGLELAAVAS
TPERQTLVGL AQPTPKYPHE VNGTPMYLYE VATESVCESA ARLLFMSIKW AKSVPAFSTL
SLQDQLMLLE DAWRELFVLG IAQWAIPVDA NTLLAVSGMN GDNTDSQKLN KIISEIQALQ
EVVARFRQLR LDATEFACLK CIVTFKAVPT HSGSELRSFR NAAAIAALQD EAQLTLNSYI
HTRYPTQPCR FGKLLLLLPA LRSISPSTIE EVFFKKTIGN VPITRLLSDM YKSSDI
//
