ID A0A2I0MW23_COLLI Unreviewed; 1329 AA.
AC A0A2I0MW23;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Zinc finger protein 521, transcript variant X1 {ECO:0000313|EMBL:PKK33861.1};
GN Name=ZNF521 {ECO:0000313|EMBL:PKK33861.1};
GN ORFNames=A306_00001547 {ECO:0000313|EMBL:PKK33861.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK33861.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK33861.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK33861.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK33861.1}.
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DR EMBL; AKCR02000001; PKK33861.1; -; Genomic_DNA.
DR RefSeq; XP_005511815.1; XM_005511758.1.
DR STRING; 8932.A0A2I0MW23; -.
DR GeneID; 102091096; -.
DR KEGG; clv:102091096; -.
DR CTD; 25925; -.
DR InParanoid; A0A2I0MW23; -.
DR OrthoDB; 3073634at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR PANTHER; PTHR24406:SF30; ZINC FINGER PROTEIN 423; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13912; zf-C2H2_6; 6.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 26.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 24.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 136..163
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 164..191
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 192..219
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 220..247
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 264..292
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 299..327
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 328..355
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 455..483
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..523
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 531..559
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 652..674
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 682..704
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 712..736
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 740..768
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 770..798
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 801..828
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 827..850
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 904..931
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 948..975
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 977..1004
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1156..1184
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1243..1270
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1274..1302
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1304..1329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1329 AA; 150318 MW; 3DF4A1986D82B046 CRC64;
MKPWGWRRRK RVEENETEDQ QAGVGHTAAQ TDPNCALEDK AEDGEVLDCK KRPDEGEELE
EEAVHSCDSC LQVFESLSDI TEHKINQCQL TDGVDVEDDP TCSWPASSPS SKDQTSPSHG
EGCDFGEEEG GPGLPYPCQF CDKSFSRLSY LKHHEQSHSD KLPFKCTYCS RLFKHKRSRD
RHIKLHTGDK KYHCSECDAA FSRSDHLKIH LKTHTSNKPY KCAICRRGFL SSSSLHGHMQ
VHERNKDGSQ SASRMEDWKM KDTQKCSQCE EGFDFPEDLQ KHIAECHPEC SPNEDRSALQ
CVYCHELFVE ETSLMNHMEQ AHNGEKKNSC SICSENFHTV EELYSHMDSH QQPESCNHSN
SPSLVTVGYT SVSSTTPDSN LSVDSSTMVE TAPPIPKGRG RKRAAQQVPD ITGPSSKQPK
VTYSCIYCNK QLFSSLAVLQ IHLKTMHLDK PEQAHICQYC LEVLPSLYNL NEHLKQVHEA
PDPALIVSTM PAMVYQCNFC SEVFNDLNTL QEHIRCSHGF ANPAAKDSNA FFCPHCYMGF
LTDSSLEEHI RQVHCDLSSS RFGSPVLGTP KDPVVEVYSC SYCTNSPIFN SVLKLNKHIK
ENHKNIPLAL NYIHNGKKSR AMSPLSPVTI EQTSLKMMQA VGGAPPRPAG EYICNQCGAK
YTSLDGFQTH LKTHLDTVLP KLTCPQCNKE FPNQESLLKH VTIHFMITST YYICESCDKQ
FTSVDDLQKH LLDMHTFVFF RCTLCQEVFD SKVSIQLHLA VKHSNEKKVY RCTSCNWDFR
NETDLQLHVK HNHLENQGKV HKCIFCGESF GTEVELQCHI TTHSKKYNCK FCSKAFHAII
LLEKHLREKH CVFETKTPNC GTNGASEQVQ KEEVELQTLL TNSQESHNSH DGSEEDVDTS
EPMYGCDICG AAYTMETLLQ NHQLRDHNIR PGESAIVKKK AELIKGNYKC NVCSRTFFSE
NGLREHMQTH LGPVKHYMCP ICGERFPSLL TLTEHKVTHS KSLDTGNCRI CKMPLQSEEE
FLEHCQMHPD LRNSLTGFRC VVCMQTVTST LELKIHGTFH MQKTGNGSAV QSTGRAQHLQ
KLYKCASCLK EFRSKQDLVK LDINGLPYGL CASCVNLSKS GSPNVNIPSS SNRQGMGQNE
NLSSIENKSK AGGLKTRCSS CNVKFESESE LQNHIQSIHR ELVPDSNSTQ LKTPQVSPMP
RISPSQTEEK KTYQCIKCQM VFYNEWDIQV HVANHMIDEG LNHECKLCNQ TFDSPAKLQC
HLIEHSFEGM GGTFKCPVCF TVFVQANKLQ QHIFSAHGQE DKIYDCTQCP QKFFFQTELQ
NHTMTQHSS
//
