ID   A0A2I0NQP5_9EURY        Unreviewed;       871 AA.
AC   A0A2I0NQP5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=PKD domain-containing protein {ECO:0000313|EMBL:PKL56317.1};
GN   ORFNames=CVV35_05390 {ECO:0000313|EMBL:PKL56317.1};
OS   Methanomicrobiales archaeon HGW-Methanomicrobiales-6.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales.
OX   NCBI_TaxID=2013822 {ECO:0000313|EMBL:PKL56317.1, ECO:0000313|Proteomes:UP000233331};
RN   [1] {ECO:0000313|EMBL:PKL56317.1, ECO:0000313|Proteomes:UP000233331}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGW-Methanomicrobiales-6 {ECO:0000313|EMBL:PKL56317.1};
RX   PubMed=28350393; DOI=10.1038/ismej.2017.39;
RA   Hernsdorf A.W., Amano Y., Miyakawa K., Ise K., Suzuki Y., Anantharaman K.,
RA   Probst A., Burstein D., Thomas B.C., Banfield J.F.;
RT   "Potential for microbial H2 and metal transformations associated with novel
RT   bacteria and archaea in deep terrestrial subsurface sediments.";
RL   ISME J. 11:1915-1929(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKL56317.1}.
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DR   EMBL; PGYH01000039; PKL56317.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0NQP5; -.
DR   Proteomes; UP000233331; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 3.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR027618; Beta_prop_Msarc.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   NCBIfam; TIGR04275; beta_prop_Msarc; 6.
DR   PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR   PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR   Pfam; PF18911; PKD_4; 3.
DR   SMART; SM00089; PKD; 3.
DR   SUPFAM; SSF49299; PKD domain; 3.
DR   SUPFAM; SSF69304; Tricorn protease N-terminal domain; 2.
DR   PROSITE; PS50093; PKD; 3.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        845..866
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          330..408
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   DOMAIN          414..485
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   DOMAIN          496..574
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          568..672
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..622
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        623..638
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        654..668
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   871 AA;  92711 MW;  7E09C023B060B59A CRC64;
     MAESKALIVA CTVIVIGLLA SPALAGERAP GDIISICIDG GSQEHPDIDG STVVWEDGRN
     GKSIYYSSSP GSGGQRVAGE GTGQRYPSVS GDYVVWEENR NMSPDICFFE ISTGVTTALT
     DDPADQWMPI VHGEHVVWYD ARGGSTDICL YTIETGSETF LSCSPVTEWK PALSERYVVW
     EESAGNGDIW LYDIWNGDKQ PITQDNWRQT YPSISGSRIV WEDYRNGAPD IYLFDLDNPA
     AGEQRITDDP AAQVSPSIDG DLIAWEDKRE GTWNVYICDL SLGKDKQMPV IPSGIEQLYP
     AVSGDRVVWQ NGRGGGSDIY AFTYFSGGAP VAEFSADPTE GGAVLIVRFI DQSAGDPDAW
     EWDFGDGNIS TSQYMWHFYE VPGNYTVSLT VHNEFGSDTV TKTDLIHVSP PEPPVISFRA
     VPLSGPAPLT VLFYGDSPNY ATAWLWDFGD GETSTHRDTR HRYDRPGVYN VSLTCDNAGA
     SATHTEYGYI TVYERLEASF SADTRNGTAP LTVRFTDTSA GEPETWAWVF GDGGTSSEQN
     PEHTYVNAGA YNVTLTTENA AGSSTAAEPG YITVHSPTPT PTPTPTPTPT PTPTPTPTPT
     PTVNVTPTPT PTPTPTVNVT PTPTPTSKPT QKSSGGGGGG GGGSSAWVDP GWNTPKPSPT
     PTPVPNTIPD DAGPGRLQIG EAGLVERVVL LGSADDIATL TIAEGVRAVD AAGNPLRAVT
     LVSLDAADVP AVPGVGAYAF TGYAWLAGPE GAAFSPPVTL SFNFTEEQWD AVYNGSGLVV
     QRYDRSMEAW EEVPTTVHPE IRSVTAVASH FNPYALFIEV PDASAAQVVA AETGPQSGTV
     PDLPYAHLIP GLLALIIVGA GALLYFRKEG A
//