ID A0A2I0P3C5_9EURY Unreviewed; 1032 AA.
AC A0A2I0P3C5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
GN ORFNames=CVV33_01175 {ECO:0000313|EMBL:PKL60726.1};
OS Methanomicrobiales archaeon HGW-Methanomicrobiales-4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales.
OX NCBI_TaxID=2013820 {ECO:0000313|EMBL:PKL60726.1, ECO:0000313|Proteomes:UP000233538};
RN [1] {ECO:0000313|EMBL:PKL60726.1, ECO:0000313|Proteomes:UP000233538}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGW-Methanomicrobiales-4 {ECO:0000313|EMBL:PKL60726.1};
RX PubMed=28350393; DOI=10.1038/ismej.2017.39;
RA Hernsdorf A.W., Amano Y., Miyakawa K., Ise K., Suzuki Y., Anantharaman K.,
RA Probst A., Burstein D., Thomas B.C., Banfield J.F.;
RT "Potential for microbial H2 and metal transformations associated with novel
RT bacteria and archaea in deep terrestrial subsurface sediments.";
RL ISME J. 11:1915-1929(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKL60726.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PGYJ01000038; PKL60726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0P3C5; -.
DR Proteomes; UP000233538; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 8.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46730:SF1; PLAT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46730; POLYCYSTIN-1; 1.
DR Pfam; PF00801; PKD; 3.
DR Pfam; PF18911; PKD_4; 3.
DR SMART; SM00089; PKD; 10.
DR SUPFAM; SSF49299; PKD domain; 10.
DR PROSITE; PS50093; PKD; 10.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 178..217
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 280..332
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 359..410
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 451..497
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 519..587
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 605..684
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 708..757
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 778..855
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 871..940
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 948..1032
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 1032 AA; 115486 MW; 86095632F846EE25 CRC64;
MWGVNEEMKN HKGFIVIPLL IIALIAVTGI VCADGFQVES APCPSANDIY QLSSDNLTFN
FTDLTPVTKR FYISDRAGIL PEYISDNYSG NLSYWDSVTE LADNFSQSPD NYLTFTFPGP
GKYLLKWVAW NGSNPDPEKC IPIPNVSTEV YAKFPINGLI NQTGSTYNYQ ARLKFNISSN
SSNPDTLDWN FGDGTSLHQT DYPNAFNHTY PSSSPYTTVN YLVNVTARNN TPLVYSDNFT
TYSLTMYPPP ASDFNITDNF THLPIGKGPA PVTADFNYNS STFDPSVIMT PEWNLSDGSA
PFSSENFTYV FDTPGVFNVT LKTSTMYGWN ITNHTLMVYD NITSNFTSVQ YPCAAFPVNV
TFRDNSSGSN RDYWAWDFGD GTSTGNTEVN WTNHTYYSPQ LYNVTLLASN KTYSISNLSS
QWIDVQGLYA NFTWDPVNRT IDRGTNGLFN FTDTSSGINI DTRWIWEFEP NKYSYIRNDS
YNFTRNGTYN VSLTVYNPNC GDSSRGNKTT KQVSVYENLY ANISYSPTCG SFPLTVQFLD
NSTDTPDTWL WRFYYLNGSY YDIPNIRNPT FVYPTPGTYQ VDLTTGNLQN KWDVRNFYVT
LTDCMQANFT ANRTRGYFPL TVNFTDVSTP SSSISSRIWN FGDQSTATQG SVDHTFSQKG
NFNVTLTVTD TTGQVKVANK TIEVGSPVYA NFTPNGSAAV PVNTSMIVQF TDLSVPQNDI
TNWNWNFDDI LPNDTNKSPF HTFTSEGLHN VTLNVSNPYY GATSVMRSQI NISVQKAPEA
GFTFSPEVVN PYEWVFFSDT SKGQEINTWL WQFGDGNTSS ETNPKYQYQN AGSYTVNLVV
SNPYGNSTAS HVVRVKGPVI ADFETDPSGW GVVNQPVTFI DTSLGQPISW IWNFGDGNTT
TTSVNPISHT YTSSGWYTIN MTGTNWDGQS GSAVRQIQIE DKARPRDVNF DVAGMKYSGV
HPLTVQFVDQ TPSQSNVTEW YWDFGDRTNA FNTTPVAPSH TYMNPGQYTV TLTVRNDAGV
NEKIRVAYVV VV
//
