ID A0A2I0P902_9EURY Unreviewed; 1044 AA.
AC A0A2I0P902;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=NgoFVII family restriction endonuclease {ECO:0000313|EMBL:PKL62711.1};
GN ORFNames=CVV31_04910 {ECO:0000313|EMBL:PKL62711.1};
OS Methanomicrobiales archaeon HGW-Methanomicrobiales-2.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales.
OX NCBI_TaxID=2013818 {ECO:0000313|EMBL:PKL62711.1, ECO:0000313|Proteomes:UP000233573};
RN [1] {ECO:0000313|EMBL:PKL62711.1, ECO:0000313|Proteomes:UP000233573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGW-Methanomicrobiales-2 {ECO:0000313|EMBL:PKL62711.1};
RX PubMed=28350393; DOI=10.1038/ismej.2017.39;
RA Hernsdorf A.W., Amano Y., Miyakawa K., Ise K., Suzuki Y., Anantharaman K.,
RA Probst A., Burstein D., Thomas B.C., Banfield J.F.;
RT "Potential for microbial H2 and metal transformations associated with novel
RT bacteria and archaea in deep terrestrial subsurface sediments.";
RL ISME J. 11:1915-1929(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKL62711.1}.
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DR EMBL; PGYL01000012; PKL62711.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0P902; -.
DR Proteomes; UP000233573; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09203; PLDc_N_DEXD_b1; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR PANTHER; PTHR47962:SF7; MITOCHONDRIAL ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:PKL62711.1};
KW Hydrolase {ECO:0000313|EMBL:PKL62711.1};
KW Nuclease {ECO:0000313|EMBL:PKL62711.1}.
FT DOMAIN 329..485
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 544..693
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1044 AA; 118339 MW; 7D6AFE9620EC7423 CRC64;
MELFPGIYEQ VISEYLASKL SGPEREGRVL KDPLSRFDPQ NVLARHIAKI LRNALMSADE
QHIPLAEQVR ICNRLIGHLA AELRDETLEQ CAITPDAEVL LALAERNPSA LKFVAPTRPE
TSIAQSSLFT GSPKEPGLVN ELRKEIQSAD RIDLLVSFIK WSGIRLILDD LKEFVRHGSR
LRVITTSYTG ATDIKAVEAL AALPNTTVRI SYDTERTRLH AKTYTFHRNS RFSTSYIGSS
NLSNPAITSG LEWNIKITEQ DSYDIIRKIE ETFETYWNDP EFVAYTPENR ERLRRALSKE
KRGEFDLRPI FDIQPYYYQK EILERLKIER EVHNNYRNLI VAATGTGKTV VSAFDYKSLI
KKPGEYPRLL FVAHREEILK QSLQVFRGVL KDQNFGDLLV GGSEPAQFDH LFTSIQSFNS
RNLPEITSPD YYDMIVVDEF HHAAAPSYQS LLTHYTPKVL LGLTATPERM DNLDILGHFN
GRVSAEIRLP EAINRKLLAP FHYFGVTDVV DLDGVPWRRG AYDPAELSRL YTGNRKRADL
ISRAVRDYTT DLDEVIGLGF CASVEHAEYM AASFREAGIP AACLHAGSPR ELRSSIQKDL
VARKIHFIFV VDLYNEGVDI PEVNTILFLR PTESLTVFIQ QLGRGLRLSD GKECLTALDF
VGNHNKNFRF GERIAALLSP GEGTLAEQVS QDSYSLPRGC YIHLEKVARE KVLANIKANR
TDKTTLIRKI QSFEVDTGEP ISFRKFLHYH SLQPLDVYRK GTFCLLAAEA GVYPAVYADE
RLFSKTAAIR LRTLNSPEAI RFIRAVLSRP SHGSPAALSD REKSVLALFY YSLNDQSLCD
ESADVRDILP EIFTHDEIRH EICDLMEYNE AHLGLLPEPV DLGFESALEL HATYTRAQAF
AALGHYTLTR RPAGGSREGV VYLEDKKADV LLITLNKTEE HYSPTTMYKD YAVNEELFHW
QSQSTTSASS PTGQRYIEHE RRGNKILLFV REYNKVDGVA QPYLFLGTAR YLSHEGSRPM
SITWKLDRPM PPGFFLKANK MVVG
//
