ID A0A2I0QZI7_9FLAO Unreviewed; 443 AA.
AC A0A2I0QZI7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN Name=rseP {ECO:0000313|EMBL:PKR79741.1};
GN ORFNames=CW751_13530 {ECO:0000313|EMBL:PKR79741.1};
OS Brumimicrobium salinarum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Crocinitomicaceae; Brumimicrobium.
OX NCBI_TaxID=2058658 {ECO:0000313|EMBL:PKR79741.1, ECO:0000313|Proteomes:UP000236654};
RN [1] {ECO:0000313|EMBL:PKR79741.1, ECO:0000313|Proteomes:UP000236654}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHR20 {ECO:0000313|EMBL:PKR79741.1,
RC ECO:0000313|Proteomes:UP000236654};
RA Do Z.-J., Luo H.-R.;
RT "The draft genome sequence of Brumimicrobium saltpan LHR20.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKR79741.1}.
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DR EMBL; PJNI01000019; PKR79741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0QZI7; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000236654; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:PKR79741.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236654};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 103..129
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 375..401
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 413..432
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 10..427
FT /note="Peptidase M50"
FT /evidence="ECO:0000259|Pfam:PF02163"
SQ SEQUENCE 443 AA; 49527 MW; 121DD1C9BA39600B CRC64;
MDFWIKAAQL ILSLAILVTV HEFGHYLAAR AFKIRVEKFY LFFDPWFSLL KKKIGDTEWG
IGWLPLGGYV KIAGMIDESM DTDQMAEPPK EDEFRSKPAW QRLIVMAAGV IVNVVVGIFI
YIMVVAAWGD NVVSNDTLKY GVAVNKNFAE LNTGIEDGDV ITAVDGEAVE NVNLINFQIF
LRGYRELEVQ QPSGEKKTIT LDKNVDDWMW ENDAVMAFSP RIPVVVDSVM ENRHAFIAGL
QKGDSITTIN GVETPFFHDL QAELAKQEGD STAVKVGFYR GGSFQEISTF TDAKKTIGFI
PKNPAWLKST HRSYTFGESI SRGIDKAIWT MHDYAAQLPL IFTSKGAQSV GGFGAIGSLF
PPAWDWEVFW ARTAFISLIL AIMNILPIPA LDGGHIVFLL YEMITGKEAP QKVLEYAQLI
GFLLLISLFL FANGNDVYRA FFK
//
