ID   A0A2I0SAZ3_9ACTN        Unreviewed;      1013 AA.
AC   A0A2I0SAZ3;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN   ORFNames=CW362_42405 {ECO:0000313|EMBL:PKT67089.1};
OS   Streptomyces populi.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2058924 {ECO:0000313|EMBL:PKT67089.1, ECO:0000313|Proteomes:UP000236178};
RN   [1] {ECO:0000313|EMBL:PKT67089.1, ECO:0000313|Proteomes:UP000236178}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A249 {ECO:0000313|EMBL:PKT67089.1,
RC   ECO:0000313|Proteomes:UP000236178};
RA   Wang Z.;
RT   "Streptomyces populusis sp. nov., a novel endophytic actinobacterium
RT   isolated from stems of Populus adenopoda Maxim.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKT67089.1}.
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DR   EMBL; PJOS01000224; PKT67089.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0SAZ3; -.
DR   OrthoDB; 3178131at2; -.
DR   Proteomes; UP000236178; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236178}.
FT   DOMAIN          945..1010
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          143..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          896..948
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        913..942
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  112110 MW;  C57BB30FF8406275 CRC64;
     MQKSAFPFHY FPFPGPLEDR SRGHPTGLDN NQAVSNSYAH NQATPRRFTH RGTQAVKLVE
     RELHLSSLKS MLAHSIAEDS RAAVLTGPVA SGKSALAQAL VEHAHDLGAQ VLQTRCSPAE
     EHLRLETVRQ LLDMRPKHNS VIEIPLGPSY SSSNPAQKPA PRRPLDPGRL TARDFGDLLL
     ELSAEIPVLI VVDDFEYADE TSAEYLSHAV RRIRSSRVMT VIATKNGPGP RTVRRTAELL
     RNPHCCPIRL RPLSRPAVGD LLTQRLGTPA KKSATDQHYA ASGGNPLLLH ALIDDLTART
     PAPRHPEHLE LTAAEHYAQA VITCLYRSTP DLTRTAAALA VLGDTPRPDL FEHLLQDPST
     TAEQALQQLT ASGTTTPGGR FRHPAARQAV LTATDTATRT ELNLRAAHWL YQRAEPAPRI
     ARHLLAAGHA REPWQTTVLR EAAAEALHRQ DTEHAVSCLE LAHTQCTDDT LRTELTIELA
     EATWPDSPLT AMRRMLPLHT QAHDRPLEHR HGLALAKTLL RSGRFDAAQD VLDRLEPTPD
     PHTSTDLYIF DKWLETSYPR FGQRFRTRPA PPPPPQPLPT GTETYLHAIE MLATVLRSDA
     HDEVITIAEE TLRNCPADDR TMEAASTLIA ALFYADRTDT LATQCDRLLT QATQRHAPAW
     QAVLSSLKAQ IAYRQGDINT TIRHARHALT AMSPQSWGVG IGVPLSSLLM GAAMAADHTT
     AEQALHHPVP ETLHETRFGI HYRHARGTYY LTTGRPQLAL RELLTCGDLM TQWHMDTPSL
     VPWRLDAAQA YLHLGRPDQA AQLLDEQTRT HPTTSNRITG MTLRLHAATQ PPHHRTPLLH
     HAITLLTPTG DRLELTRALA DQTHTHTHTG NTTAAHHTRR QTLDLINQSG ATALHTLLQP
     QPPTPHTDTP QPTRTNPPAT THTNTGTGTG TGTGTTPHTG TTQPHPRDHH LLSTAEHRVA
     TLVARGYTNR QVARHLYITN STVEQHMTRV YRKLNITRRT DLPTWLTHPH TNT
//