ID A0A2I0WVE1_9ASPA Unreviewed; 1296 AA.
AC A0A2I0WVE1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=MA16_Dca026834 {ECO:0000313|EMBL:PKU79630.1};
OS Dendrobium catenatum.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Epidendroideae; Malaxideae; Dendrobiinae; Dendrobium.
OX NCBI_TaxID=906689 {ECO:0000313|EMBL:PKU79630.1, ECO:0000313|Proteomes:UP000233837};
RN [1] {ECO:0000313|EMBL:PKU79630.1, ECO:0000313|Proteomes:UP000233837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=The whole plant {ECO:0000313|EMBL:PKU79630.1};
RX PubMed=26754549; DOI=10.1038/srep19029;
RA Zhang G.Q., Xu Q., Bian C., Tsai W.C., Yeh C.M., Liu K.W., Yoshida K.,
RA Zhang L.S., Chang S.B., Chen F., Shi Y., Su Y.Y., Zhang Y.Q., Chen L.J.,
RA Yin Y., Lin M., Huang H., Deng H., Wang Z.W., Zhu S.L., Zhao X., Deng C.,
RA Niu S.C., Huang J., Wang M., Liu G.H., Yang H.J., Xiao X.J., Hsiao Y.Y.,
RA Wu W.L., Chen Y.Y., Mitsuda N., Ohme-Takagi M., Luo Y.B., Van de Peer Y.,
RA Liu Z.J.;
RT "The Dendrobium catenatum Lindl. genome sequence provides insights into
RT polysaccharide synthase, floral development and adaptive evolution.";
RL Sci. Rep. 6:19029-19029(2016).
RN [2] {ECO:0000313|EMBL:PKU79630.1, ECO:0000313|Proteomes:UP000233837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=The whole plant {ECO:0000313|EMBL:PKU79630.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
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DR EMBL; KZ502437; PKU79630.1; -; Genomic_DNA.
DR Proteomes; UP000233837; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR35046:SF19; RNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR35046; ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Reference proteome {ECO:0000313|Proteomes:UP000233837};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 163..179
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 477..656
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 990..1153
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 97..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1296 AA; 147814 MW; A103720BA6DD6C7C CRC64;
MKQLLRGHFL PTDYEQMLYL RYQHCVQGLR TVNEYTEEFY RLSARNNLQE TENQLVARFV
GGLREQLQEK LEMNSIWSLS QAVNFALKAE AQLQRHSRSY SSRRLVSQES PGDNSRTATT
NAYAKPPTAP GNTPIVQATE PRPPIRAKIP PKENPYGRPN PLKCFRCFQP GHKSNECPNR
QQLQLAEGEN REFSGEPELP AEKDDETEDV CGDMGEPLVC ILEKLLLAPR HAVPTQRNAL
FRTKCTIQGK VCELLVDSGC TENVISRSVV QALQLKTTKK SHPYKISWVK RGIEITVNET
CAVTFSIGKH YVCNVVCDVL DMDVCHIILG RPWQFDANAH YDCRSNVYSL EWNGKKLRLL
PQTPEHIGQN EKGKAVAYLV SGPELLLTPL AETTMLALVT TDFQNVHDKV PLPAGIRSLL
QEFADIVPSE LPMELPPLRA IQHQIDFVPG STLPNLPHHR MSPKEHQILQ EIVDDLLRRQ
LIQHSMSPCA VPALIVPKKD GQWRLCIDSR AINKITTKYR FPVPRISDLL DKLHGSVVFS
KLDLRSGYHQ VRIRSGDEWK TAFKTREGLY EWRVMPFGLC NAPSTFMRLM AEVLKPFSGK
FCVSYFDDIL IFSPSMEEHL QHLHQVFAAL RAHKLYLNMS KCEFGNPSVC FLGFIISHEG
IHADPRKIAA IRDWPVPRSI TDVRSFHGLA NFYRRFIKGF SVIAAPLTDL MKGNSFAWTD
PQQTSFDQIK NALCNAPVLA LPSFEKAFQV DTDASGTGIG AVLYQEERPV EYFSEKLSPS
RQKWTVYEQE LYAVVRALKQ WEHYLLHQDF VLCSDHQSLQ YLNSQKTINK MHARWVIFLQ
KFSFVVKYKT GKLNRVADAL SRRAALLTRL QTEVTGMQEM KALYAEDTDF GSIWESCCFG
TPQDDFSVRH GFLFKGNSLC VPESSWRQQL IKDIHCGGLA AHVGRDRTLQ QLQCKFFWPH
MRRDVARFVE RCAVCQQYKG TAQNTGLYLP LPVPDTIWED LSLDFVLGLP RTTRGSDSIM
VVVDRFSKMA HFVACKKTFD ALHIAKLFFK EIVRLHGISR SLTSDRDVKF ISHFWRELWK
RFQTDLKMSS AYHPQTDGQT EVTNRTLASM LRCLVEDHPK RWEEVLGQAE FAYNSMPNRA
TGMCPFSIVY TKMPNHIVDV AVLPKCRSAA AAQSAEQFSE ILKSVRGRLE DTNLKYKAAQ
DKHRRSVEFQ PGDLVMLRYR QDRFPVGSCP KLHPKKFGPF PILRKINDNA YVIDLPKDLA
ISTTFNVADI YPYHPPDEAV TALHSSEMSS SETGGN
//
