ID A0A2I1DL09_9PROT Unreviewed; 752 AA.
AC A0A2I1DL09;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:PKY10570.1};
GN ORFNames=B1757_08290 {ECO:0000313|EMBL:PKY10570.1};
OS Acidithiobacillus marinus.
OC Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=187490 {ECO:0000313|EMBL:PKY10570.1, ECO:0000313|Proteomes:UP000234329};
RN [1] {ECO:0000313|EMBL:PKY10570.1, ECO:0000313|Proteomes:UP000234329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH {ECO:0000313|EMBL:PKY10570.1,
RC ECO:0000313|Proteomes:UP000234329};
RA Sharmin S., Tokuhisa M., Kanao T., Kamimura K.;
RT "Draft genime sequence of the acidophilic sulfur-oxidizing bacterium
RT Acidithiobacillus sp. SH, isolated from seawater.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKY10570.1}.
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DR EMBL; MXAV01000034; PKY10570.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I1DL09; -.
DR InParanoid; A0A2I1DL09; -.
DR OrthoDB; 5287200at2; -.
DR Proteomes; UP000234329; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:PKY10570.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:PKY10570.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000234329};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 145..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 83246 MW; C8AF68BE571EAB2C CRC64;
MIDKALEKSI NQAFQIARQY GHEYASVEHL LLALLDNPEG QEVLRACGGN TVHLSMELQN
FLERKVPAMG PAGTVNTQPS VGFQRVIQRA LYHVQSAGKE AVSGANVIVA MFAERESHAV
YFLQKEHVTR LDVVNYLAHG LRKDEAMDEE EEEIEGNTEK KGNSKDPLQA YARNLNAMAR
AGRLDPLIGR QDEVIRALQV LARRRKNNPL FVGEPGVGKT AIVEGIARAI VAGKVPELLE
DVTIYALDLG ALIAGSRYRG DFEERLKAVL KALRKQPGSI LFIDEIHTLI GAGAASGGAM
DASNLLKPAL ASGELKCIGA TTYQEFRQYF EKDRALTRRF QKIDVPEPSQ EESVQILRGL
KSQFEQHHHL RYTDTALRAA VELSVKHIHD RHLPDKAIDL IDEVGAAQAL LPPSKRKKSI
GIHDIEEMVA RVVRIPGKKV SLDDRQALKN LERDLGLVIY GQEKAIQELS SAIKMARAGL
RHHEKPVGTF LFSGPTGVGK TELSRQLASL LGIPLLRFDM SEYMERHTVS RLIGAPPGYV
GHDQAGQLTE AVSRNPHSVL LLDEIEKAHP DIFNVLLQVM DHGKLTDAGG RSVDFRHVVL
IMTTNAGAES RNKASIGFMK PAEKEGGQEM ETIRRIFSPE FRNRLDAVVP FSALSRENIL
HVVDKFIMEL DEQLLGKGYS LEISPELRQW LADKGYDPQM GARPMARVIQ EHLKKPLAEH
ILFGDLPKGT RITATLEEGA VTLQIPEAVS AE
//
