ID A0A2I1EFH5_9GLOM Unreviewed; 414 AA.
AC A0A2I1EFH5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Medium-chain specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000256|ARBA:ARBA00019125};
GN ORFNames=CHRIB12_LOCUS12331 {ECO:0000313|EMBL:CAB5369811.1},
GN RhiirA1_425771 {ECO:0000313|EMBL:PKC60572.1}, RhiirA4_407499
GN {ECO:0000313|EMBL:PKY51520.1}, RhiirA5_349712
GN {ECO:0000313|EMBL:PKC14916.1}, RhiirC2_749589
GN {ECO:0000313|EMBL:PKK68785.1};
OS Rhizophagus irregularis.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX NCBI_TaxID=588596 {ECO:0000313|EMBL:PKY51520.1, ECO:0000313|Proteomes:UP000234323};
RN [1] {ECO:0000313|EMBL:PKY51520.1, ECO:0000313|Proteomes:UP000234323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A4 {ECO:0000313|EMBL:PKY51520.1,
RC ECO:0000313|Proteomes:UP000234323}, A5 {ECO:0000313|EMBL:PKC14916.1,
RC ECO:0000313|Proteomes:UP000232722}, and C2
RC {ECO:0000313|EMBL:PKK68785.1, ECO:0000313|Proteomes:UP000233469};
RA Ropars J., Sedzielewska K., Noel J., Charron P., Farinelli L., Marton T.,
RA Kruger M., Pelin A., Brachmann A., Corradi N.;
RT "Genome analyses suggest a sexual origin of heterokaryosis in a supposedly
RT ancient asexual fungus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PKC14916.1, ECO:0000313|Proteomes:UP000232722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A5 {ECO:0000313|EMBL:PKC14916.1,
RC ECO:0000313|Proteomes:UP000232722};
RA Chen E.C., Morin E., Beaudet D., Noel J., Ndikumana S., Charron P.,
RA St-Onge C., Giorgi J., Grigoriev I.V., Roux C., Martin F.M., Corradi N.;
RT "Extensive intraspecific genome diversity in a model arbuscular mycorrhizal
RT fungus.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000232688, ECO:0000313|Proteomes:UP000233469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1 {ECO:0000313|EMBL:PKC60572.1,
RC ECO:0000313|Proteomes:UP000232688}, and C2
RC {ECO:0000313|EMBL:PKK68785.1, ECO:0000313|Proteomes:UP000233469};
RA Chen E.C.H., Morin E., Baudet D., Noel J., Ndikumana S., Charron P.,
RA St-Onge C., Giorgi J., Grigoriev I.V., Roux C., Martin F.M., Corradi N.;
RT "Extensive intraspecific genome diversity in a model arbuscular mycorrhizal
RT fungus.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:PKC60572.1, ECO:0000313|Proteomes:UP000232688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1 {ECO:0000313|EMBL:PKC60572.1,
RC ECO:0000313|Proteomes:UP000232688};
RA Corradi N., Sedzielewska K., Noel J., Charron P., Farinelli L., Marton T.,
RA Kruger M., Pelin A., Brachmann A., Corradi N.;
RT "Genome analyses suggest a sexual origin of heterokaryosis in a supposedly
RT ancient asexual fungus.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:CAB5369811.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CHB12 {ECO:0000313|EMBL:CAB5369811.1};
RA Rincon C., Sanders R I., Robbins C., Chaturvedi A.;
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362125};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347, ECO:0000256|RuleBase:RU362125}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKY51520.1}.
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DR EMBL; CAGKOT010000027; CAB5369811.1; -; Genomic_DNA.
DR EMBL; LLXJ01000111; PKC14916.1; -; Genomic_DNA.
DR EMBL; LLXH01001127; PKC60572.1; -; Genomic_DNA.
DR EMBL; LLXL01000802; PKK68785.1; -; Genomic_DNA.
DR EMBL; LLXI01001036; PKY51520.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FUN_019576; -.
DR VEuPathDB; FungiDB:GLOIN_2v1714515; -.
DR VEuPathDB; FungiDB:RhiirA1_425771; -.
DR OMA; KCHAADV; -.
DR OrthoDB; 275353at2759; -.
DR Proteomes; UP000232688; Unassembled WGS sequence.
DR Proteomes; UP000232722; Unassembled WGS sequence.
DR Proteomes; UP000233469; Unassembled WGS sequence.
DR Proteomes; UP000234323; Unassembled WGS sequence.
DR Proteomes; UP000684084; Unassembled WGS sequence.
DR GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR006089; Acyl-CoA_DH_CS.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR48083:SF2; MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48083; MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR PIRSF; PIRSF016578; HsaA; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR PROSITE; PS00072; ACYL_COA_DH_1; 1.
DR PROSITE; PS00073; ACYL_COA_DH_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362125};
KW Oxidoreductase {ECO:0000256|RuleBase:RU362125};
KW Reference proteome {ECO:0000313|Proteomes:UP000234323}.
FT DOMAIN 36..145
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 151..247
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 259..407
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 414 AA; 44942 MW; 6A14E4F8CB922E5D CRC64;
MLRPIFHSTT IRSALALAAR TFTSTVSAGG PTFALTEEQQ GFQELARKFA HEEIAPKAAH
HDRTGEYPTE IIKKAWELGL VNTHIPTEFG GLGFGVFDSS LITEELAWGC TGIQTAIEAN
GLAEAPLLVA GNKEQNKKYL GRMTEEPLMA AYCVTEPGAG SDVAGIITKA EKRGDKWVIN
GQKMWITNGG KANWYFILAR SDPTAKAGSA FTGFIVDANT PGISLGKKEI NLGQRASDTR
GVTFEEVVVP QENVLGSPGQ GFKIAMAAFD ITRPLIAAGA VGLARRAMEE ALKYSLERKT
MGQTIFNYQS VAFMLADAAI GIEAARNMVW KSAWLRDQNQ RNTYYASIAK ALASDVAVTT
ASNAIQIFGG NGFNTEYPVE KLYRDSKIFQ IYEGTSQIQR LIISRHLAEN AANM
//
