ID A0A2I1GJ02_9GLOM Unreviewed; 849 AA.
AC A0A2I1GJ02;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DUF221-domain-containing protein {ECO:0000313|EMBL:PKY46571.1};
GN ORFNames=RhiirA4_520050 {ECO:0000313|EMBL:PKY46571.1};
OS Rhizophagus irregularis.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX NCBI_TaxID=588596 {ECO:0000313|EMBL:PKY46571.1, ECO:0000313|Proteomes:UP000234323};
RN [1] {ECO:0000313|EMBL:PKY46571.1, ECO:0000313|Proteomes:UP000234323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A4 {ECO:0000313|EMBL:PKY46571.1,
RC ECO:0000313|Proteomes:UP000234323};
RA Ropars J., Sedzielewska K., Noel J., Charron P., Farinelli L., Marton T.,
RA Kruger M., Pelin A., Brachmann A., Corradi N.;
RT "Genome analyses suggest a sexual origin of heterokaryosis in a supposedly
RT ancient asexual fungus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKY46571.1}.
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DR EMBL; LLXI01000463; PKY46571.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I1GJ02; -.
DR VEuPathDB; FungiDB:FUN_018785; -.
DR VEuPathDB; FungiDB:GLOIN_2v1656080; -.
DR VEuPathDB; FungiDB:RhiirA1_350669; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000234323; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF143; PHOSPHATE METABOLISM PROTEIN 7; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000234323};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..165
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 189..358
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 369..646
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 738..806
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 705..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 849 AA; 96140 MW; CB34F8436ADA1F7F CRC64;
MSQDPASQQQ STDSSIATFT SSLVFNVAVT IGIFVAFDIL RKRNKKVYEP RTYLVPESNR
SEPLPPGLFA WILPVLKISD EEVIKRIGLD SYMFLRFMKL FMILFAIFSI FGLAVLLPIN
SVNQGDNQGL EKFTIGNIRD NKRLWSHVIF TWLFSGITMY ALYREFNTFI RLRHEYHTTD
EYRNSPRATT ILVTGIPKEL NNSESLKALF DIFPGGVKRI WLNRDPSKLA KATAKREAVV
NNLEGAATNY IIQYAKDSTK PEFRESNVEN GNSPNIKRPQ HSSKLPIIGK KVDSLETYSN
DLNDINHQIS ELQKNPNNFK RLNSAFIQFN DYVGAQLAAT STVPKLINIS PDDIIWENLN
LTSKQRMIRR VISLSVVIGI VIIWMSAVTF VAGISTLSEL AKLKPLNFLE GLNNAGGNLK
VLVGIIQGIL PAVALNILMM ILVIVLRFLS RFEGNVTNSG VDLSLQSKYY FHLVMNVLLV
TTFANGILQS LPKLVNNPTQ SIEILANNLP RASTFFLTYI LLTITACALE IFQIGPLIMN
FFFKKFLVKT PRKIWELEKT MPFQDWGTGF PPHIMIASIG IVYSTIQPII LPIVTLHFAL
YYLVYRHQFL YVYDKLNQTG GLLFPKAIYQ VFTGIYIFQL TLTGLMFLNG GFVQGVLCII
LLVLSVGVLL AMKLIFKHNP RAEFLPVDLM GVIDMKTRNL LVGKNQDKQI SSEKEPIRND
DDDDDDDDDD YTRADVLHIN EGDEKDLDDD YGASTFTHPA LVAIQPSVWI PNDQNVSNDM
VNEFRKDGIK STNQGASLDK NHKVIIDLGK IPLEFRDDQY AKSKKANKKR EVKQLKKQID
EIEEEIGER
//
