ID   A0A2I1K951_9LACT        Unreviewed;       493 AA.
AC   A0A2I1K951;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Threonine synthase {ECO:0000313|EMBL:PKY92144.1};
GN   ORFNames=CYJ27_01535 {ECO:0000313|EMBL:PKY92144.1};
OS   Aerococcus christensenii.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Aerococcus.
OX   NCBI_TaxID=87541 {ECO:0000313|EMBL:PKY92144.1, ECO:0000313|Proteomes:UP000234775};
RN   [1] {ECO:0000313|EMBL:PKY92144.1, ECO:0000313|Proteomes:UP000234775}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UMB0844 {ECO:0000313|EMBL:PKY92144.1,
RC   ECO:0000313|Proteomes:UP000234775};
RA   Thomas-White K., Wolfe A.J.;
RT   "Phylogenetic diversity of female urinary microbiome.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR604450-51};
CC   -!- SIMILARITY: Belongs to the threonine synthase family.
CC       {ECO:0000256|ARBA:ARBA00005517}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKY92144.1}.
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DR   EMBL; PKGZ01000001; PKY92144.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I1K951; -.
DR   Proteomes; UP000234775; Unassembled WGS sequence.
DR   CDD; cd01560; Thr-synth_2; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR   InterPro; IPR029144; Thr_synth_N.
DR   InterPro; IPR037158; Thr_synth_N_sf.
DR   InterPro; IPR004450; Thr_synthase-like.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   NCBIfam; TIGR00260; thrC; 1.
DR   PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR   PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF14821; Thr_synth_N; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR604450-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000234775}.
FT   DOMAIN          3..78
FT                   /note="Threonine synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14821"
FT   DOMAIN          99..418
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
FT   MOD_RES         110
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ   SEQUENCE   493 AA;  55403 MW;  2B9669ECBC78FDE4 CRC64;
     MLYTSTRDNR IRITASQAIL QGLSEDGGLY VPVDFPRINR TWQEVKNYTY QEMAEWVLGL
     FLTDFSAESI KACVQAAYGE NFDDERMAPL VQVGDHYHLE LFHGQTIAFK DMALSILPHL
     MKKAAKMNHN TNESVILTAT SGDTGKAAMA GFKDVIGTKI IVFYPKGGVS SIQERQMITQ
     EGENTYVIAV EGNFDDAQNQ VKKLFNDVSL REKLAQEGCQ FSSANSMNIG RLLPQIVYYF
     YAYAQLLKEG QIKEGEKINF TVPTGNFGNI LAAYYAKKMG LPVDKLVCAS NDNTVLYDLF
     QTGTYDRCRP FKLTISPSMD ILISSNFERL LYYAVGENSE EVKEYMDALN LKGSYHLSDE
     VRKQLSDFVG EYASEEETLK EIGTVYTKEG YLMDPHTAVA SVCGHKAKKG LKGKNIIVST
     ASPYKFPEAI LKALAVENPE TDRERLEFIH QKSGIAFPPT ITALFQAPVR HRMEATVEEM
     KDYVLAIIHQ KKK
//