ID A0A2I2A587_9GAMM Unreviewed; 580 AA.
AC A0A2I2A587;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=L-ornithine N(alpha)-acyltransferase {ECO:0000256|ARBA:ARBA00039866};
DE EC=2.3.2.30 {ECO:0000256|ARBA:ARBA00039058};
GN ORFNames=CYQ88_05570 {ECO:0000313|EMBL:PLA74549.1};
OS Hydrogenovibrio sp. SC-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Hydrogenovibrio.
OX NCBI_TaxID=2065820 {ECO:0000313|EMBL:PLA74549.1, ECO:0000313|Proteomes:UP000234529};
RN [1] {ECO:0000313|Proteomes:UP000234529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-1 {ECO:0000313|Proteomes:UP000234529};
RA Barco R.A., Emerson D.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + L-ornithine = a lyso-ornithine
CC lipid + H(+) + holo-[ACP]; Xref=Rhea:RHEA:20633, Rhea:RHEA-COMP:9685,
CC Rhea:RHEA-COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:64479, ChEBI:CHEBI:78827, ChEBI:CHEBI:138482;
CC EC=2.3.2.30; Evidence={ECO:0000256|ARBA:ARBA00036203};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20634;
CC Evidence={ECO:0000256|ARBA:ARBA00036203};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. OlsB subfamily.
CC {ECO:0000256|ARBA:ARBA00038095}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLA74549.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PKGB01000007; PLA74549.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I2A587; -.
DR OrthoDB; 1113830at2; -.
DR Proteomes; UP000234529; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07986; LPLAT_ACT14924-like; 1.
DR InterPro; IPR045746; ACT14924-like_Acyltransf_dom.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR37323; GCN5-RELATED N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR37323:SF1; L-ORNITHINE N(ALPHA)-ACYLTRANSFERASE; 1.
DR Pfam; PF13444; Acetyltransf_5; 1.
DR Pfam; PF19576; Acyltransf_2; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Reference proteome {ECO:0000313|Proteomes:UP000234529};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PLA74549.1}.
FT DOMAIN 80..198
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 580 AA; 66300 MW; 56DB4923A5B2915D CRC64;
MLDIQKTILE KYPDFPSKPG GKKLIQFLQK LTYEKEINQF IEENQHLRGF AFLDKCLNHF
NFSYQVNHRA LDAIPSEGRV IMVANHPIGS LDGLALLKMI RSIRPDVRIV ANELLSHVEP
FQSLFLSVDN MSSKANHKAH FKAMIAALEN EEAVIIFPAG EVSRIRPNGV RDSQWKHGFL
KLAKKTQSPI LPIYIDARNS ILFYGLSTLY KPLGTLMLVQ EMFNKKNQQV AFHVGALVPW
KSLADCNWPY PKMAKYFRKH IYRLNDPQVA AENFVFKTEN TLAHPVNRTA LKKDLKNGEL
LGETADGKKI FLFDYEADSA VMQEIGRLRE LTFRTVEEGT GDAFDLDKYD ASYRHLVLWD
EEDLEIVGAY RLGDCRKIVE EKGLSGLYTS TLFTLKPEMT PYLNNALELG RSFVQPRYWG
KRSLDYLWYG IGAYVNRHPE TTYLFGPVSL SDAFPTRAKE LIVAFFQTQM GSKQDLAIGK
RPFIPSPEIK AIAEQDFDED YNTSYKKLNI LLSEEGVKVP TLFKQYADLC EPGGCRFIDF
SVDPDFNDCI DSLILIEIDK IKPKKQARYL KNNATTLKTA
//
