ID   A0A2I2G562_9EURO        Unreviewed;       665 AA.
AC   A0A2I2G562;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Permease of the major facilitator superfamily {ECO:0000313|EMBL:PLB48020.1};
GN   ORFNames=P170DRAFT_203115 {ECO:0000313|EMBL:PLB48020.1};
OS   Aspergillus steynii IBT 23096.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=1392250 {ECO:0000313|EMBL:PLB48020.1, ECO:0000313|Proteomes:UP000234275};
RN   [1] {ECO:0000313|EMBL:PLB48020.1, ECO:0000313|Proteomes:UP000234275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 23096 {ECO:0000313|EMBL:PLB48020.1,
RC   ECO:0000313|Proteomes:UP000234275};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC       transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PLB48020.1}.
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DR   EMBL; MSFO01000005; PLB48020.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I2G562; -.
DR   STRING; 1392250.A0A2I2G562; -.
DR   VEuPathDB; FungiDB:P170DRAFT_203115; -.
DR   OrthoDB; 37768at2759; -.
DR   Proteomes; UP000234275; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR24064:SF235; PHOSPHATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10690)-RELATED; 1.
DR   PANTHER; PTHR24064; SOLUTE CARRIER FAMILY 22 MEMBER; 1.
DR   Pfam; PF00083; Sugar_tr; 2.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000234275};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        169..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        382..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        507..525
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          94..529
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          632..665
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  75097 MW;  95586E61FC7E1777 CRC64;
     MTDFGPRAPH GPDMSGTHQP LENMDINEKG AFDALIRPED SYTPDGTYWA DLSFFRRVKF
     VGSYDAGEAK RELGSIWEMT KQDPLSPISY YFRNMVLPGA GLGLEGYVLF SIGNLKPLFQ
     AAFKSCWDDK EICNAHWLDA IDYLEICGII VGQILVGILG DWLGRRWGLI QDAAIMFIGL
     LMLTAAWGVT QNGWVICYAW SLFFYGIGVG GEYPMTATSG MENAVGSGKV STKEDRLHRG
     RKVTSAFLMQ GWGQFFNQVL LIILLLCFHH GSGNPPYSSV SAQWTYRISF AIPAVGTLWL
     VYYRAYHMKA ASKQLASAKK KASVTGYDFN SLRLTFHHFG FRILATAGGW FANDVFFYGN
     KLFQSEFIKV ISPASDSIMP TWLWNLVNVG VSLVGYYCAS FLIDNKLYGR KWMQMIGFMM
     CFILFIVPAF NYEYYTSPEH IHEFQAMYFL SSFFNQFGPN SVTFLVAAEV FPTPIRATAH
     GLSAAAGKSG ALLASVLYNY IDTQTKFYVV PWFGLAGMVL TLIFLPDTTG LDLKEQERRW
     TYIRDGREHE YHGPAVHSKH LSIWERITGK GKHYDAEADY KSKVEEYRAE WETAMSRKVA
     EQNKGEELEM DTDDSLLEGH VHAYFHRTSP MFRPMEQTAK SDNFALPPAA QDGDSSDSFN
     EKSEK
//