ID A0A2I2GFZ7_9EURO Unreviewed; 1571 AA.
AC A0A2I2GFZ7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Myosin class V heavy chain {ECO:0008006|Google:ProtNLM};
GN ORFNames=P170DRAFT_433649 {ECO:0000313|EMBL:PLB51780.1};
OS Aspergillus steynii IBT 23096.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=1392250 {ECO:0000313|EMBL:PLB51780.1, ECO:0000313|Proteomes:UP000234275};
RN [1] {ECO:0000313|EMBL:PLB51780.1, ECO:0000313|Proteomes:UP000234275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 23096 {ECO:0000313|EMBL:PLB51780.1,
RC ECO:0000313|Proteomes:UP000234275};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLB51780.1}.
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DR EMBL; MSFO01000002; PLB51780.1; -; Genomic_DNA.
DR STRING; 1392250.A0A2I2GFZ7; -.
DR VEuPathDB; FungiDB:P170DRAFT_433649; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000234275; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000234275}.
FT DOMAIN 6..59
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 74..780
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1231..1500
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 915..1078
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1571 AA; 179551 MW; 1EB868F1E02413B1 CRC64;
MAHNYEVGTR AWQPDPTEGW IASEVKEKSV DGDKVQLVFL MENGESKTVE TTQAELQLDN
NSRLPPLMNP AMLEASEDLT NLSHLNEPAV LQAIKLRYAQ KEIYTYSGIV LIATNPFARV
DSLYVPQMVQ VYAGKHRASQ APHLFAIAEE AFADMLRDGK NQTIVVSGES GAGKTVSAKY
IMRYFATRES SDQPGKYTTS RAEAISETEE QILATNPVME AFGNAKTTRN DNSSRFGKYI
EIMFDDRTNI IGAKIRTYLL ERSRLVFQPL KERNYHVFYQ LVAGATDDEK QELGLGSVED
FDYLNQGGTP TIDGVDDKTE FNATRKSLST IGVSDKTQSE IFRILAALLH LGNVKITATR
TDSTLSPSEP GLVKACDLFG IDANEFAKWI VKKQLITRGE KITSNLTQQQ ATVVRDSVAK
FIYSSLFDWL VDKINRGLAT DQVMSQFKAF IGVLDIYGFE HFAKNSFEQF CINYANEKLQ
QEFNQHVFKL EQEEYVREQI DWTFIDFSDN QPCIDLIEAK LGILSLLDEE SRLPMGSDEQ
FVTKLHHNFA ADKQKFYKKP RFGKSAFTIC HYAVDVTYES DGFIEKNRDT VPDEHMEILR
NSSNEFVKEI LDTAAAVREK DSASISSKPV AAPGRKIGVA VNRKPTLGGI FKSSLIELMN
TINSTDVHYI RCIKPNEAKE AWKFEGPMVL SQLRACGVLE TVRISTAGYP TRWTYEEFAI
RYYMLCHSSQ WTSEIREMCH AILQKALGDG SHKKQDKYQL GLTKIFFRAG MLAFLENLRT
SRLNECAIMI QKNLRCKYYR RRYLEARASI LTTQALIRGF LARQHAAEVR QVKAATTIQR
VWRGQKERKR YNRIRENFVL FQSVAKGFLC RRNIMDTIHG NAAKVIQRSF RSWRQLRAWR
QYRRNVVIIQ SLWRGREART EYKRLREDAR DLKQISYKLE NKVVELTQYL ESLKRENRSL
NSQLENYETQ VKSWRSRHNA LENRTRELQA EANQAGITAA RLTAMEEEMS LLRQNHHEAQ
ATIKRLQEEE KVSRESILAA NQELEGLRHL NNEAESEKVS LRQQVADLEE QLELAKRTMP
VNGLNGEQQN GGSVQPPASG LINLVSSKKP KPKRRSAGAE KIETDRFSGA YNPRPVSMAI
PSTLARQNFS NTTFSPGLDS VEVELENLLS EEDELNEEVT MGLIRNLKIP LPSSTPPPTE
KEVLFPAYLI NLVTSEMWNN GFVKESERFL ANVMQSIQQE VMQHDGDDAV NPGAFWLSNV
HEMLSFVFLA EDWYEAQKTD NYEYDRLLEI VKHDLESLEF NIYHTWMKVL KKKLFKMIVP
AIIESQSLPG FVTSETNRFL GKLLPSNNNP AYSMDNLLSL LNNVYKAMKA FYLEDSIIIQ
TVTELLRLVG VTAFNDLLMR RNFLSWKRGL QINYNITRIE EWCKSHDMPE GTLQLEHLMQ
ATKLLQLKKA TLNDIEIIQD ICWMLSPNQI QKLLNQYLVA DYEQPINGEI MKAVASRVTE
KSDVLLLTPV DMEDSGPYEI ADPRVITALE TYTPSWLQTP RLKRLAEIVS AQAMAQQERL
EMAENGSMAA E
//
