ID A0A2I2GNB1_9EURO Unreviewed; 1124 AA.
AC A0A2I2GNB1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DENN-domain-containing protein {ECO:0000313|EMBL:PLB54364.1};
GN ORFNames=P170DRAFT_442472 {ECO:0000313|EMBL:PLB54364.1};
OS Aspergillus steynii IBT 23096.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=1392250 {ECO:0000313|EMBL:PLB54364.1, ECO:0000313|Proteomes:UP000234275};
RN [1] {ECO:0000313|EMBL:PLB54364.1, ECO:0000313|Proteomes:UP000234275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 23096 {ECO:0000313|EMBL:PLB54364.1,
RC ECO:0000313|Proteomes:UP000234275};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLB54364.1}.
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DR EMBL; MSFO01000001; PLB54364.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I2GNB1; -.
DR VEuPathDB; FungiDB:P170DRAFT_442472; -.
DR OrthoDB; 1331806at2759; -.
DR Proteomes; UP000234275; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR12296:SF21; DENN DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000234275};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 237..1011
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT DOMAIN 878..925
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT REGION 64..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..775
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 124678 MW; 109F0BF72E9E91AB CRC64;
MPFSSSSSSS TPEVSTTPLA DYFWIAGVDG TEILDTFQRL GDEYRANNAT SPGPAVTDTI
EEDADAEEAH DPRLDGLSRP NSMAGGRNSF QRFSMRSGDP DANENGSSSN RSSMTIKGAQ
SPRGSSFLED FDFDKALLKF ASERDSFLSD LSHTAGAITP QSQARPRSRL RTQKIISEES
PSQPSSLLRS GIGSVRRHMA FRDMNSMKRQ PSVARQASIR TSRRLSNYNS VIPVPQPLEI
SPSMHPLKRR FEPVLLDRYP TRNMSDELKQ RGNFPDYVPM FAFPNDINIV SSDQRPRSTW
HGFAMTTDNG SRLHAICVII WIPLNQRAAE ELEKRCEEWR KDNMTDEERE LAASLGERLA
SERAKLSRLL AQLPTVPSGS ESREQLEDEI SAVEEKIGLM TDLLRPVRHG AASKIEGLTD
GDTGFWIPRA YGILGREENM TSFWKEWLKA VIVPMTDGSI QRVPPSSPRM GIWQPLERYV
MNLCTEAFSP NTSKTQVELA VRELRLFARK EASNELPGAR NTDIYALFRT LSLSNIVILL
EYALTESRII FLSSHTSMLY LATKALVDLL FPIPWSGVLI PVLPARLVQA IEAPCPYIVG
IERRYEKVEL PSDDFVLVDL DADLIESTIQ PTPLPRHQRR KLLSLLQLAA PHHGRFGVPT
GPPAYAIETF PFDAFSSENS SIFNSRAQST QLAKYVSLNS SAFGQSSVPP SSYQPLVFNA
YLHARYEQVP SRGYSSKGSD RPGTGSTSKT GSPPSPRDIS PTSGHFPPPP PTPNSRNDSG
LALQASLREK RSGHFDAASR RSSSFGMEMR QGVPRRPSAP FLGHAPNLSV TTLNTDYNSG
STYAPSVYAQ STVAASTIVP QASNQPIHNS EGTCWVEGHC LRLQPCDEKA VCAICDERAE
EGMYRCTACK TLVHNRCALQ ICLVCPAAFH PEQVRAAFVR LFASLFYTYK KYLQPASGDK
KKAGLTYSFN MDAFMKSLPG EHAEYISILQ QTQGFNEFIS EREHVNPKSR DPRMALFDEI
VLSKRNRGRS SIFSSRSMTD FLSDTSNHLW RTASATSFGP GSRGQQNLSG DYTRVVTRAP
AKLDTSLMKE PRMIHGAPRV SKTANNARRK PLPKLMNGLA ISPP
//
