ID A0A2I2GSE2_9EURO Unreviewed; 1370 AA.
AC A0A2I2GSE2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Dynactin {ECO:0000313|EMBL:PLB55795.1};
GN ORFNames=P170DRAFT_400217 {ECO:0000313|EMBL:PLB55795.1};
OS Aspergillus steynii IBT 23096.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=1392250 {ECO:0000313|EMBL:PLB55795.1, ECO:0000313|Proteomes:UP000234275};
RN [1] {ECO:0000313|EMBL:PLB55795.1, ECO:0000313|Proteomes:UP000234275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 23096 {ECO:0000313|EMBL:PLB55795.1,
RC ECO:0000313|Proteomes:UP000234275};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PLB55795.1}.
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DR EMBL; MSFO01000001; PLB55795.1; -; Genomic_DNA.
DR STRING; 1392250.A0A2I2GSE2; -.
DR VEuPathDB; FungiDB:P170DRAFT_400217; -.
DR OrthoDB; 9423at2759; -.
DR Proteomes; UP000234275; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000234275}.
FT DOMAIN 23..65
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 74..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1206..1231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1311..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1035..1135
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 121..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1370 AA; 152450 MW; C88D4F3EA9D23AC1 CRC64;
MEQSIGNVVT LTDGRQATVR FIGTTHFSPG DWIGIELDEP TGKNDGSIQG EQYFECEPGF
GMFVRKTAIK ATVAQQPARD AKPAAKGSTN VPPANRGRAQ SGVAAAGTGI KKVGAAPAAN
TKRHSASSAS PTPASKVAAQ RLSLKPPAKS PTKQMSGAST PLSHRSSISG TSRPSVAPPK
LRPAAGKSSM GPPPPPSAAT RTSRPSISGP ATRTTRQNTL DSASTPAGIA KRPVLRPAAT
NKPSEEPDSG ASPNSEAFES GSQQDIDEDA PQIEEPAPKT SRAITGPARA SAGRPSLSSP
SSSQRQGQNG AVARELEELK TKLRVMEKKR TEDREKLKSL EKLQSDRDKY ESIIQKLQAK
YQPQQAEIGD LRKKLKESEA RLEEVERLQA EHESIMEMAT LDREMAEETS DAFRHECDAL
RGKVEELQLE VEVLREENEE FGQVMSPEEK SSHGWLQMEK TNERLREALL RLRDMTQQQE
QELREQVKEM EQDLEDYAAV KSQYESTKEK LLVSENNVED LKQQLETALG AEEMIEELAD
KNMRYQEEIN ELHAAIEDLE ALKEINDELE YNHIETEKQL QEEIDYREGL FNEQCRKITQ
QDEVIDDLEY TLVRFRELVS TLQGDLEDMR ASQQISEAEA TDLTTRSRAM MDLNLKLQAS
VTKTQTKTID IEIGHMEAEE ATQHLSILKL YLPEYFEGER NSILALLRFK RVGFKSSLMN
STIREKLSEQ ASIPAGLEDT FTAYDVLEKL SWIASLCDRF VAYISNCSTD AFGNMKATLF
EMEPVERTLN FWLEFLKKDE VNMKKCGTEL QRSIALISHL AETYLPSSLE VFSGELCMRS
SLTQSYIDHA ASSVGRLRAL LLSKISAPEG DEEINFLSNK MEGFVSHARG LKVAMGKVNR
SLEDLRSRSL SLSQDVSGPF KKTEEAAKEL AELTRHLGEN IVHLLSDESR TEPLSLEEAS
RNMSQISTLY AGPSESGSES SDTMSFIFNR LRSLGGNLEE LESISSDLSI TSEFEKHPNP
WIARAAELKS SKTSSPDADE EIRRLKNEIN EASTALGVKD KTIEEQTIKV ETVEARMRDA
TKKASMVKEL EAKIEEMRTK ETELEALVEQ QRKELQDMEA EREEIKARLD RVKRASGTTG
VATTDGIVVD AGASLATMRE NEALRAEVES LQAAVRYLRE ENRRANILDP YSIQRSAELH
SWLDVPLTQP SSSSSTLPNP QEKTHQTASE SRDVFTHLLK LTTESNICDL KSTLPSTDPV
TRTGWRPSKT KLRYQVLQQR ENLSRWTEWK DDVVSQEREQ DRLAASRKER LALGRGGGRG
HAPRNSVFGG FPQGTGHGMM GRAWEILGMQ QDRKTGDGGR SVEPVIADSF
//
