ID   A0A2I2KKP4_9ACTN        Unreviewed;       221 AA.
AC   A0A2I2KKP4;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SNQ46240.1};
GN   ORFNames=FRACA_1300011 {ECO:0000313|EMBL:SNQ46240.1};
OS   Frankia canadensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=1836972 {ECO:0000313|EMBL:SNQ46240.1, ECO:0000313|Proteomes:UP000234331};
RN   [1] {ECO:0000313|EMBL:SNQ46240.1, ECO:0000313|Proteomes:UP000234331}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FRACA_ARgP5 {ECO:0000313|EMBL:SNQ46240.1};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZMO01000036; SNQ46240.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I2KKP4; -.
DR   Proteomes; UP000234331; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000234331};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          8..68
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        31..50
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   221 AA;  23962 MW;  3B3EA2A2FBC32B06 CRC64;
     MAVQIDQGRE REQIMNAAYR CLIASEGASV SITDILQAAG LSTRAFYRHF ASKDSLLLAM
     FRRDSERVTA ELSAAAAGTL TAAEALRSWI DGALRLMSQE PRRRRALVLS SDEARRARGY
     AGEREWYHAT SEAALAAILR RGVEDGSFPW ANPEADAEQI QAILGYCLDT QLLRRPADGD
     ARLAERAGEL ADRVGDFIFR ALGAAPGPTP RADTGGGADP R
//