ID A0A2I2KTA4_9ACTN Unreviewed; 661 AA.
AC A0A2I2KTA4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Serine/threonine protein kinase with FHA domain {ECO:0000313|EMBL:SNQ48876.1};
GN ORFNames=FRACA_2880004 {ECO:0000313|EMBL:SNQ48876.1};
OS Frankia canadensis.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=1836972 {ECO:0000313|EMBL:SNQ48876.1, ECO:0000313|Proteomes:UP000234331};
RN [1] {ECO:0000313|EMBL:SNQ48876.1, ECO:0000313|Proteomes:UP000234331}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRACA_ARgP5 {ECO:0000313|EMBL:SNQ48876.1};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FZMO01000210; SNQ48876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I2KTA4; -.
DR Proteomes; UP000234331; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR48041:SF91; ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A; 1.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:SNQ48876.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000234331};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:SNQ48876.1};
KW Transferase {ECO:0000313|EMBL:SNQ48876.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 404..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..50
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 86..319
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 345..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 70125 MW; 1792C7CFD21920E4 CRC64;
MVIGRAPECD VMLDDPLVSR RHAELRQAGS GWRIVDLGSW NGTFVNGRRV GEATVSTDDI
VGIGHALLRL QGGTLVEYTD EGDISFEADD LVVTRSGKRL LDGVGFALGR RSLLAVVGPS
GAGKSTLLGA LTGQRPADSG EVRYAGRDLY ASYDELRQRI GLVPQDDILH SQLTVRRALR
YAAELRFPAD TPAAERHARV EEVIGELGLT DQAAQRISTL SGGQRKRTSV ALELLTRPSL
LFLDEPTSGL DPGMDKSVMQ TLRTLADDGR TVVVVTHSPA QLDVCDRLLV LAAGGRLAYF
GPPGEALAYF GERDFADMFL LLDRDRNVDW TARFRASPYH AKYGMPGSSA RPASGPASGG
PGGPGGRTSA RPGVGSAEPA RPVPDLPPRQ QPALRQFSAL ARRYLAVIAA DRAYALFLLA
LPLVLSLFAQ LLPGRHGLSV AATGTGDEGI GTMMVVLVLG CVFTGFAGAF RELVKERSVF
HREQSIGLSR GAYLWSKLVV LGLITGLQAV ILAVVGLAGQ PGPDTPVVLR GSGLAEVTVA
LVVVSVAAMV LGLLVSALIA NADRGMPILV VILLLQFLLG GTLIPLHGHP PLEQLGDLMP
ARWGLAMVGA TTKFNPKSDP MWENDAGTWG IDLAAALLLT VTLAGSTWYA LRRGAAPRRG
R
//
