ID A0A2I2KVI9_9ACTN Unreviewed; 460 AA.
AC A0A2I2KVI9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Glutamate--methylamine ligase {ECO:0000313|EMBL:SNQ49675.1};
DE EC=6.3.4.12 {ECO:0000313|EMBL:SNQ49675.1};
GN ORFNames=FRACA_360027 {ECO:0000313|EMBL:SNQ49675.1};
OS Frankia canadensis.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=1836972 {ECO:0000313|EMBL:SNQ49675.1, ECO:0000313|Proteomes:UP000234331};
RN [1] {ECO:0000313|EMBL:SNQ49675.1, ECO:0000313|Proteomes:UP000234331}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRACA_ARgP5 {ECO:0000313|EMBL:SNQ49675.1};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; FZMO01000290; SNQ49675.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I2KVI9; -.
DR Proteomes; UP000234331; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR017536; Glutamine_synthetase_typeIII.
DR NCBIfam; TIGR03105; gln_synth_III; 1.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF12; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE PUUA; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:SNQ49675.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000234331}.
FT DOMAIN 22..106
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 112..460
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 460 AA; 48464 MW; D23C2EB96C6B6EE1 CRC64;
MIESTVTETA SGASLAERAA ADGTSFVLAT FVDLDGKPCA KLVPAAALDR AQTDGVGFAG
FAAGGTGQVP SDPDLIARPD PDSYVALPFV RPGLAMVQCD PHVEGEPWPY APRIILRRMC
ERLATEGRSL RVGAECEYFL VERRDDGTIV PADAADRSAR PCYDARDLTR MYEHLTDVST
ALNTLGWDNY ANDHEDGNGQ FEQNFAHADA LTTADRVIAF RYLVRMIAER RGMVATFMPK
PFSGLTGSGM HLHVSLWAGE RALFPDPDDP RGLGLSELAY GFVGGVLGHA PALLALLTPT
VNSFKRTGAA TPSSGATWTP TRATYGGNDR THLVRVPDGD RVEIRVVDGA ANPYLAIAGL
IAAGLDGVDA KLDPGPVGGP GRPGGIGTTP VPGAAGGELP PTLLHAVEAF VADPVITGAL
AAAGAGGDVP AYYAARRRAE FLDWHSQVGG WEIDRYLTAF
//
