ID A0A2I2UD17_FELCA Unreviewed; 587 AA.
AC A0A2I2UD17;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Ring finger protein 38 {ECO:0000313|Ensembl:ENSFCAP00000030378.3};
GN Name=RNF38 {ECO:0000313|Ensembl:ENSFCAP00000030378.3,
GN ECO:0000313|VGNC:VGNC:64701};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000030378.3, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000030378.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000030378.3,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000030378.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000030378.3,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000030378.3}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000030378.3};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04001372; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2UD17; -.
DR Ensembl; ENSFCAT00000043809.3; ENSFCAP00000030378.3; ENSFCAG00000023701.4.
DR VGNC; VGNC:64701; RNF38.
DR GeneTree; ENSGT00940000156228; -.
DR Proteomes; UP000011712; Chromosome D4.
DR Bgee; ENSFCAG00000023701; Expressed in testis and 10 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16679; RING-H2_RNF38; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46171:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF38; 1.
DR PANTHER; PTHR46171; GH10160P; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 535..576
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..56
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 64203 MW; 018CBBBA8DA49478 CRC64;
MSGSAAAAVA AAASAAAAAA HFQPQSSSPR PGAAELGPLR RPRPPPPPPR PEPAAAGRLS
PPGHGPLRAG SQGGGACGRA PGAGSVGASF QCQSIHHDHI CHDDSDKISP GANSAPLPGH
PNKVICERVK LQSLFPLLPS DQNTTVQEDA HFKAFFQSED SPSPKRQRLS HSVFDYTSAS
PAPSPPMRPW EMTSNRQPPS VRSSQHHFSG ERCNTPARNR RSPPVRRQRG RRDRLSRHNS
ISQDENYHHL PYAQQQAIEE PRAFHPPNVS PRLLHPAAHP PQQNAVMVDI HDQLHQGTVP
VSYTVTTVAP HGIPLCTGQH IPACSTQQVP GCSVVFSGQH LPVCSVPPPM LQACSVQHLP
VPYAAFPPLI SSDPFLLHPP HLSPHHPPHL PPPGQFVPFQ TQQSRSPLQR IENEVELLGE
HLPEVSFGVP YPPFMPRRLT GRSRYRSQQP IPPPPYHPSL LPYVLSMLPV PPAVGPTFSF
ELDVEDGEVE NYEALLNLAE RLGEAKPRGL TKADIEQLPS YRFNPNNHQS EQTLCVVCMC
DFESRQLLRV LPCNHEFHAK CVDKWLKANR TCPICRADAS EVHRDSE
//
