ID A0A2I2UHH4_FELCA Unreviewed; 520 AA.
AC A0A2I2UHH4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 2.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Tetratricopeptide repeat domain 6 {ECO:0000313|Ensembl:ENSFCAP00000031779.2};
GN Name=TTC6 {ECO:0000313|Ensembl:ENSFCAP00000031779.2,
GN ECO:0000313|VGNC:VGNC:82513};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000031779.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000031779.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000031779.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000031779.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000031779.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000031779.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000031779.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04004459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2UHH4; -.
DR Ensembl; ENSFCAT00000040979.3; ENSFCAP00000031779.2; ENSFCAG00000004443.6.
DR VGNC; VGNC:82513; TTC6.
DR GeneTree; ENSGT00940000161150; -.
DR OMA; AIRYKPD; -.
DR Proteomes; UP000011712; Chromosome B3.
DR Bgee; ENSFCAG00000004443; Expressed in testis.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44858; TETRATRICOPEPTIDE REPEAT PROTEIN 6; 1.
DR PANTHER; PTHR44858:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 13.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 57..90
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 176..209
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 281..314
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 348..381
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 382..415
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 450..483
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 520 AA; 59332 MW; 559621852274789E CRC64;
MMKCYDLAKF TIYQVAEMNK GLIELSPIQQ ALIYSFCENH DKAIQVLDRI TLNRPELTMY
TLLAKAQMKA KKIKEAMRMF KKALDIFSHS DKGPNAVAAS ADCLYNLGLC YMEEGNIQMT
YKLAITDLTT AINMDKNSYI AFYNRALCYT KISELRMALT DYGIVLLLDA GETVMLNTFI
NRGLIYVELE QYTFALEDFK QAALISKTNV SLCQATAMCH HRNKEFEEAV DFFTWALKID
PCFLDAYVGR GNSYMEYGHA EATKQAQKDF LKVLRINPTY TKARISLGYN LQAQGKFQKA
WNHFTVAIEV DPKCYLAYEG RAVVSLQMGD NFAAIQDINA AIKINTTAEF LTNRGVIHEF
MGQQQNAMKD YQAAISLNPT YSLAYFNAGN IYFHHRQFSQ ASDYFSKALK FDPENECAAM
NRAIANTILK KYKEAKEDFA YVVESCPFWA AVYFNRAHFY CCLKQYELAE GDLSRALSLK
PDDALIYNRR AEVRGRIGLI EEAVADYIQA LDLQEYSPVM
//
