ID A0A2I2UV79_FELCA Unreviewed; 153 AA.
AC A0A2I2UV79;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Coiled-coil-helix-coiled-coil-helix domain containing 2 {ECO:0000313|Ensembl:ENSFCAP00000036448.1};
GN Name=CHCHD2 {ECO:0000313|Ensembl:ENSFCAP00000036448.1};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000036448.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000036448.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036448.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000036448.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036448.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000036448.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036448.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04004562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003998658.1; XM_003998609.4.
DR AlphaFoldDB; A0A2I2UV79; -.
DR STRING; 9685.ENSFCAP00000036448; -.
DR PaxDb; 9685-ENSFCAP00000019821; -.
DR Ensembl; ENSFCAT00000033108.3; ENSFCAP00000036448.1; ENSFCAG00000036807.3.
DR GeneID; 101080932; -.
DR KEGG; fca:101080932; -.
DR CTD; 51142; -.
DR GeneTree; ENSGT00440000038159; -.
DR InParanoid; A0A2I2UV79; -.
DR OMA; CDADARN; -.
DR OrthoDB; 2912282at2759; -.
DR Proteomes; UP000011712; Chromosome E3.
DR Bgee; ENSFCAG00000036807; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0140297; F:DNA-binding transcription factor binding; IEA:Ensembl.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR GO; GO:1905448; P:positive regulation of mitochondrial ATP synthesis coupled electron transport; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:1900037; P:regulation of cellular response to hypoxia; IEA:Ensembl.
DR InterPro; IPR010625; CHCH.
DR PANTHER; PTHR13523; COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77; 1.
DR PANTHER; PTHR13523:SF3; COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED; 1.
DR Pfam; PF06747; CHCH; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 116..148
FT /note="CHCH"
FT /evidence="ECO:0000259|Pfam:PF06747"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 153 AA; 15769 MW; E8E6484F43A63021 CRC64;
MPRGSRSRTS RMAPPASRAP QMRAAPRPAP AAQPPAAAPP SAVGSPAAAP RQPGLMAQMA
TTAAGVAVGS AVGHTLGHAI TGGFGGGSNA EPSRPDITYQ EPQGTQPAYQ QQFGPCHYEM
KQFLECAQNQ GDLKLCEGFS EVLKQCRFAN GLA
//
