ID A0A2I2UWP5_FELCA Unreviewed; 1490 AA.
AC A0A2I2UWP5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=WD repeat domain 7 {ECO:0000313|Ensembl:ENSFCAP00000036965.2};
GN Name=WDR7 {ECO:0000313|Ensembl:ENSFCAP00000036965.2,
GN ECO:0000313|VGNC:VGNC:67049};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000036965.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000036965.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036965.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000036965.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036965.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000036965.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000036965.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9685.ENSFCAP00000036965; -.
DR PaxDb; 9685-ENSFCAP00000010605; -.
DR Ensembl; ENSFCAT00000046868.3; ENSFCAP00000036965.2; ENSFCAG00000011414.6.
DR VGNC; VGNC:67049; WDR7.
DR GeneTree; ENSGT00940000155301; -.
DR InParanoid; A0A2I2UWP5; -.
DR OMA; DKVCESQ; -.
DR Proteomes; UP000011712; Chromosome D3.
DR Bgee; ENSFCAG00000011414; Expressed in brain and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44099; RABCONNECTIN-3B, ISOFORM A; 1.
DR PANTHER; PTHR44099:SF3; WD REPEAT-CONTAINING PROTEIN 7; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 22..49
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 460..507
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 556..597
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1390..1426
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 761..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 911..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..947
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1490 AA; 163784 MW; 2FE912B69089B92F CRC64;
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GTTIVTGCHD GQICLWDLSV ELEVNPRALL
FGHTASITCL SKACASTDKQ YIVSASESGE MCLWDVNDGR CIEFTKLACT HTGIQFYQFS
VGNQKEGRLL CHGHYPEILV VDATSLEVLY SLVSKISPDW ISSMSIIRSH RTQEDTVVAL
SVTGILKVWI VTSEISGMQD TEPIFEEESK PIYCQNCQSI SFCAFTQRSL LVVCSKYWRV
FDAGDYSLLC SGPSENGQTW TGGDFVSADK VIIWTENGQS YIYRLPASCL PASDSFRSDV
GKAVENLIPP VQHSLLDRTD KELLICPPVT RFFYGCREHI HKLLIQGDSS GRLNIWNISD
TPDKQEGKEE LKMTTSISLQ EAFDKLNPCP AGIIDQLSVI PNSSEPLKVT ASVYIPAHGR
LVCGREDGSI IIVPATQTAI VQLLQGEHML RRGWPPHRTL RGHRNKVTCL LYPHQVSARY
DQRYLISGGV DFSVIIWDIF SGEMKHIFCV HGGEITQLLV PPENCSARVQ HCICSVASDH
SVGLLSLREK KCIMLASRHL FPVQVIKWRP SDDYLVVGCS DGSVYVWQMD TGALDRCVMG
ITAVEILNAC DEAVPAAADS LSHPAINLKQ AMTRRSLAAL KNMAHHKLQT LATNLLASEA
SDKGNLPKYS HNSLMVQAIK TNLTDPDIHV LFFDVEALII QLLTEEASRP NTALISPENL
QKASGSSDKG GSFLTGKRAA VLFQQVKETI KENIKEHLLD DEEEDEEIMR QRREESDPEY
RASKSKPLTL LEYNLTMDTA KLFMSCLHAW GLNEVLDEVC LDRLGMLKPH CTVSFGLLSR
GGHMSLMLPG YNQPARKLSH GKAEVGRKLP AAEGAGKGTY GVSRAVTTQH LLSIISLANT
LMSMTNATFI GDHMKKGPTR PPRPSTPDLS KARGSPPTSS NIVQGQIKQV PAPVISARSD
ADHSGSDPAS TPALHTCFLV NEGWSQLAAM HCVMLPDLLG LDKFRPPLLE MLARRWQDRC
LEVREAAQAL LLAELRRIEQ AGRKEAIDAW APYLPQYMDH VISPGVSAEA MQTIGTAPDA
LGPEAKVQEE EHDLADDDIT TGCLSSIPQM KKISTSYEER RKQATAIVLL GVIGAEFGAE
IEPPKLLTRP RSSSQIPEGF GLTSGGSNYS LARHTCKALT FLLLQPPSPK LPPHSTIRRT
AIDLIGRGFT VWEPYMDVSA VLMGLLELCA DAEKQLANIT MGLPLSPAAD SARSARHALS
LIATARPPAF ITTIAKEVHR HTALAANTQS QQSVHTTALA RAKGEVLRVI EILIEKMPTD
VVDLLVEVMD IIMYCLEGSL VKKKGLQECF PAICRFYMVS YYERNHRIAV GARHGSVALY
DIRTGKCQTI HGHKGPITAV AFAPDGRYLA TYSNTDSHIS FWQMNTSLLG SIGMLNSAPQ
LRCIKTYQVP PVQPASPGSH NALRLARLIW TSNRNVILMA HDGKEHRFMV
//
