ID A0A2I2UZB7_FELCA Unreviewed; 588 AA.
AC A0A2I2UZB7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 2.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat and SOCS box containing 15 {ECO:0000313|Ensembl:ENSFCAP00000037655.2};
GN Name=ASB15 {ECO:0000313|VGNC:VGNC:69352};
GN Synonyms=LMOD2 {ECO:0000313|Ensembl:ENSFCAP00000037655.2};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000037655.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000037655.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037655.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000037655.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037655.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000037655.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037655.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AANG04000096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003983038.1; XM_003982989.3.
DR RefSeq; XP_019681311.1; XM_019825752.1.
DR RefSeq; XP_019681312.1; XM_019825753.1.
DR AlphaFoldDB; A0A2I2UZB7; -.
DR PaxDb; 9685-ENSFCAP00000004143; -.
DR Ensembl; ENSFCAT00000042982.3; ENSFCAP00000037655.2; ENSFCAG00000004489.6.
DR GeneID; 101092756; -.
DR KEGG; fca:101092756; -.
DR CTD; 142685; -.
DR VGNC; VGNC:69352; ASB15.
DR GeneTree; ENSGT00940000156567; -.
DR OMA; HVNDTHF; -.
DR OrthoDB; 5479200at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000011712; Chromosome A2.
DR Bgee; ENSFCAG00000004489; Expressed in testis and 4 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24198:SF187; SOCS BOX DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 8.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 110..142
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 143..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 176..208
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 209..241
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 242..274
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 307..339
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 349..381
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 379..407
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 533..579
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 588 AA; 65996 MW; B9DBCB46171C1BE2 CRC64;
MDTNDDPDED HLTSYDIQLS IQESIEASKS VFSSERFVPL SDQNRKLVEA IKQGHILELQ
EYVKYKHALD EADEKGWFPL HEAVVQPIQQ ILEVVLDASY QTLWEFKTSE GETPLTLAVK
AGLVENVRTL LEKGVWPNTK NDKGETPLLI AVKKGSYDMV FTLLKHNASL DQPCIKRWSA
MHEAAKQGRK DIIALLLNHG GNVHLRDGFG VTPLGVAAEY GHCDVLEHLI HRGGDVFALA
DDGASVLFEA AGGGNPDCIS LLLEYGGSGN VPNRAGHLPI HRAAYEGHYL ALKYLIPITS
KNAIQKSGLT PIHSAADGQN VQCLELLIEN GFDVNTLLAD HISESYDDER KTALYFAVSN
NDIQCTEVLL AAGADPNLDP LNCLLVAVRA NNHEIVRLLL SHGANVNCYF MRVNDTRFPS
AIQYALNDEV MLRLLLNNGY QVEMCFDCMH GNIFGNSFVW SEIEEEVLPG WTSCVIKDNP
FCEFITVPWM KHLVGSVIRV LIDYMDYIPL CAKLKSALQV QREWPEIRQI LENPCSLKHL
CRLKIRRLMG LQRLCQPASM EKLPLPPTIR RYILFKEYDL YGQELKLP
//
