ID A0A2I2V1T8_FELCA Unreviewed; 195 AA.
AC A0A2I2V1T8;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Peroxisomal membrane protein 2 {ECO:0008006|Google:ProtNLM};
GN Name=PGAM5 {ECO:0000313|Ensembl:ENSFCAP00000038707.1};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000038707.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000038707.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000038707.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000038707.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000038707.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000038707.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000038707.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000256|ARBA:ARBA00006824, ECO:0000256|RuleBase:RU363053}.
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DR EMBL; AANG04003227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2V1T8; -.
DR PaxDb; 9685-ENSFCAP00000002300; -.
DR Ensembl; ENSFCAT00000041072.3; ENSFCAP00000038707.1; ENSFCAG00000002503.5.
DR GeneTree; ENSGT00390000004796; -.
DR OMA; CAPTMIG; -.
DR Proteomes; UP000011712; Chromosome D3.
DR Bgee; ENSFCAG00000002503; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR11266:SF80; PEROXISOMAL MEMBRANE PROTEIN 2; 1.
DR PANTHER; PTHR11266; PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363053};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363053};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363053}.
FT TRANSMEM 31..52
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 114..132
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 172..189
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
SQ SEQUENCE 195 AA; 22349 MW; 88A2DBC3CB297289 CRC64;
MASAASKLRA EAGLGALPQR ALVQYLRLLR LYPVLTKAAT SGILSALGNF LAQMMAKQRK
KENCQKLDVS GPLRYAIYGF FFTGPLSHFF YLFMEHWIPS EVPWAGVKRL LLDRLLFAPA
FLLLFLLVMN FLEGRDAAAL SVQIRRSFWP ALRMNWRVWT PVQFININYV PLQFRVLVAN
LVSLFWYIYL ASLGK
//
