ID A0A2I2V393_FELCA Unreviewed; 458 AA.
AC A0A2I2V393;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
GN Name=LRRFIP2 {ECO:0000313|Ensembl:ENSFCAP00000039218.3,
GN ECO:0000313|VGNC:VGNC:68094};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000039218.3, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000039218.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000039218.3,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000039218.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000039218.3,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000039218.3}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000039218.3};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
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DR EMBL; AANG04001816; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2V393; -.
DR Ensembl; ENSFCAT00000043849.3; ENSFCAP00000039218.3; ENSFCAG00000001374.6.
DR VGNC; VGNC:68094; LRRFIP2.
DR GeneTree; ENSGT00530000063564; -.
DR Proteomes; UP000011712; Chromosome C2.
DR Bgee; ENSFCAG00000001374; Expressed in testis and 10 other cell types or tissues.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR Pfam; PF09738; LRRFIP; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 133..247
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 307..450
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 52322 MW; 8D1AA17F8C9BBC88 CRC64;
MGTPGSGRKR TPVKDRFSAE DEALSNIARE AEARLAAKRA ARAEARDIRM RELERQQKEL
DEKSDKQYAE NYTRPSSRNS ASATTPLSGN SSRRGSGDTS SLVDPDTSLS ELRDIYDLKD
QIQDVEGRYM QGLKELKESL SEVEEKYKKA MVSNAQLDNE KNNLIYQVDT LKDVIEEQEE
QMAEFYRENE EKSKELERQK HMCSVLQHKM DELKEGLRQR DELIEALEKQ REYIACLRNE
RDALREQLAD PKETVKTGEK HGLVIIPDGT PNGDVHHEPV VGAITVVSQE AAQVLESAGE
GPLDVRLRKL AGEKEELLSQ IRRLKLQLEE ERQRCSRSES TAADLAGLHN GSDLQFIDMQ
RDANRQISEY KFKLSKAEQD ITTLEQNVSR LEGQVLRYKT AAENAEKVED ELKAEKRKLQ
RELRTALDKI EEVEMTNSHL AKRLEKMKAN RTALLAQQ
//
