ID A0A2I2YK70_GORGO Unreviewed; 186 AA.
AC A0A2I2YK70;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 12B {ECO:0000313|Ensembl:ENSGGOP00000035325.1};
GN Name=PPP1R12B {ECO:0000313|Ensembl:ENSGGOP00000035325.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000035325.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000035325.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000035325.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000035325.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030008327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030008335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004028218.1; XM_004028169.2.
DR AlphaFoldDB; A0A2I2YK70; -.
DR Ensembl; ENSGGOT00000051240.1; ENSGGOP00000035325.1; ENSGGOG00000004481.3.
DR GeneTree; ENSGT00940000157067; -.
DR Proteomes; UP000001519; Chromosome 1.
DR Bgee; ENSGGOG00000004481; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR Gene3D; 6.10.250.1820; -; 1.
DR InterPro; IPR031775; PRKG1_interact.
DR PANTHER; PTHR24179; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12; 1.
DR PANTHER; PTHR24179:SF18; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B; 1.
DR Pfam; PF15898; PRKG1_interact; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 85..186
FT /note="cGMP-dependent protein kinase interacting"
FT /evidence="ECO:0000259|Pfam:PF15898"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 186 AA; 21379 MW; A38E01A345BA647C CRC64;
MSSLYTRSKE FTRNRKSQSD SPPASPSPTA KTLRHERLSR LESGGSNPTT SDSYGDRASA
RARREAREAR LAILTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE LADIKSKLEK
VAQQKQEKTS DRSSVLEMEK RERRALERKM SEMEEEMKVL TELKSDNQRL KDENGALIRV
ISKLSK
//
