ID A0A2I2YU63_GORGO Unreviewed; 363 AA.
AC A0A2I2YU63;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Protein NDRG3 {ECO:0000256|ARBA:ARBA00015425};
DE AltName: Full=N-myc downstream-regulated gene 3 protein {ECO:0000256|ARBA:ARBA00030207};
GN Name=NDRG3 {ECO:0000313|Ensembl:ENSGGOP00000038438.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000038438.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000038438.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000038438.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000038438.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NDRG family.
CC {ECO:0000256|ARBA:ARBA00005598}.
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DR EMBL; CABD030116655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030116656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030116657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030116658; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030116659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030116660; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2YU63; -.
DR Ensembl; ENSGGOT00000052077.1; ENSGGOP00000038438.1; ENSGGOG00000012893.3.
DR GeneTree; ENSGT00950000182872; -.
DR Proteomes; UP000001519; Chromosome 20.
DR Bgee; ENSGGOG00000012893; Expressed in frontal cortex and 6 other cell types or tissues.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR004142; NDRG.
DR PANTHER; PTHR11034; N-MYC DOWNSTREAM REGULATED; 1.
DR PANTHER; PTHR11034:SF20; PROTEIN NDRG3; 1.
DR Pfam; PF03096; Ndr; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT REGION 314..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 40220 MW; 528DF494C7C9DFBF CRC64;
MDELQDVQLT EIKPLLNDKN GTRNFQDFDC QEHDIETTHG VVHVTIRGLP KGNRPVILTY
HDIGLNHKSC FNAFFNFEDM QEITQHFAVC HVDAPGQQEG APSFPTGYQY PTMDELAEML
PPVLTHLSLK SIIGIGVGAG AYILSRFAVS IDRVSPCWSE FLSFQLSGLT TNVVDIILAH
HFGQEELQAN LDLIQTYRMH IAQDINQDNL QLFLNSYNGR RDLEIERPIL GQNDNKSKTL
KCSTLLVVGD NSPAVEAVVE CNSRLNPINT TLLKMADCGG LPQVVQPGKL TEAFKYFLQG
MGYIPSASMT RLARSRTHST SSSLGSGESP FSRSVTSNQS DGTQESCESP DVLDRHQTME
VSC
//
