ID A0A2I2YV56_GORGO Unreviewed; 1847 AA.
AC A0A2I2YV56;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger protein 236 {ECO:0000313|Ensembl:ENSGGOP00000038617.1};
GN Name=ZNF236 {ECO:0000313|Ensembl:ENSGGOP00000038617.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000038617.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000038617.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000038617.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000038617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030110270; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110271; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110272; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110274; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030110276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018869786.1; XM_019014241.1.
DR Ensembl; ENSGGOT00000051811.1; ENSGGOP00000038617.1; ENSGGOG00000008826.3.
DR GeneID; 101138818; -.
DR KEGG; ggo:101138818; -.
DR CTD; 7776; -.
DR GeneTree; ENSGT00940000156787; -.
DR OrthoDB; 5390050at2759; -.
DR Proteomes; UP000001519; Chromosome 18.
DR Bgee; ENSGGOG00000008826; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 26.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24396; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24396:SF21; ZINC FINGER PROTEIN 236; 1.
DR Pfam; PF00096; zf-C2H2; 18.
DR Pfam; PF13912; zf-C2H2_6; 3.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 16.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 30.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 30.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 39..67
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 68..95
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 95..122
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 123..150
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 155..182
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 199..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 255..283
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 287..315
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 484..511
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 512..539
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 540..567
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 568..598
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 659..686
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 687..714
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 715..742
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 743..770
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 969..996
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 997..1024
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1025..1052
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1053..1075
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1169..1196
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1197..1224
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1225..1252
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1253..1280
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1659..1687
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1688..1715
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1724..1751
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1752..1779
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1780..1804
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1269..1299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1847 AA; 203898 MW; C668BB771811F6BC CRC64;
MPRGRPPKPR ESKARGDSDG VLTLNAENTN YAYQVPNFHK CEICLLSFPK ESQFQRHMRD
HERNDKPHRC DQCPQTFNVE FNLTLHKCTH SGEDPTCPVC NKKFSRVASL KAHIMLHEKE
ENLICSECGD EFTLQSQLAV HMEEHRQELA GTRQHACKAC KKEFETSSEL KEHMKTHYKI
RVSSTRSYNR NIDRSGFTYS CPHCGKTFQK PSQLTRHIRI HTGERPFKCS ECGKAFNQKG
ALQTHMIKHT GEKPHACAFC PAAFSQKGNL QSHVQRVHSE VKNGPTYNCT ECSCVFKSLG
SLNTHISKMH MGGPQNSTSS TETAHVLTAT LFQTLPLQQT EAQPTSASSQ PSSQAVSDVI
QQLLELSEPA PVESGQSPQP GQQLSITVGI NQDILQQALE NSGLSSIPAA AHPNDSCHAK
TSAPHAQNPD VSSVSNEQTD PTDAEQEKGQ ESPEKLDKKE KKMIKKKSPF LPGSIREENG
VRWHVCPYCA KEFRKPSDLV RHIRIHTHEK PFKCPQCFRA FAVKSTLTAH IKTHTGIKAF
KCQYCMKSFS TSGSLKVHIR LHTGVRPFAC PHCDKKFRTS GHRKTHIASH FKHTELRKMR
HQRKPAKVRV GKTNVPVPDI PLQEPILITD LGLIQPIPKN QFFQSYFNNN FVNEADRPYK
CFYCHRAYKK SCHLKQHIRS HTGEKPFKCS QCGRGFVSAG VLKAHIRTHT GLKSFKCLIC
NGAFTTGGSL RRHMGIHNDL RPYMCPYCQK TFKTSLNCKK HMKTHRYELA QQLQQHQQAA
SIDDSTVDQQ SMQASTQMQV EIESDELPQT AEVVAANPEA MLDLEPQHVV GTEEAGLGQQ
LADQPLEADE DGFVAPQDPL RGHIDQFEEQ TPAQQSFEPA GLPQGFTVTD TYHQQPQFPP
VQQLQDSSTL ESQALSTSFH QQSLLQAPSS DGMNVTTRLI QESSQEELDL QPQGSQFLED
NEDQSRRSYR CDYCNKGFKK SSHLKQHVRS HTGEKPYKCK LCGRGFVSSG VLKSHEKTHT
GVKAFSCSVC NASFTTNGSL TRHMATHMSM KPYKCPFCEE GFRTTVHCKK HMKRHQTVPS
AVSATGETEG GDICMEEEEE HSDRNASRKS RPEVITFTEE ETAQLAKIRP QESATVSEKV
LVQSAAEKDR ISELRDKQAE LQDEPKHANC CTYCPKSFKK PSDLVRHVRI HTGEKPYKCD
ECGKSFTVKS TLDCHVKTHT GQKLFSCHVC SNAFSTKGSL KVHMRLHTGA KPFKCPHCEL
RFRTSGRRKT HMQFHYKPDP KKARKPMTRS SSEGLQPVNL LNSSSTDPNV FIMNNSVLTG
QFDQNLLQPG LVGQAILPAS VSAGGDLTVS LTDGSLATLE GIQLQLAANL VGPNVQISGI
DAASINNITL QIDPSILQQT LQQGNLLAQQ LTGEPGLAPQ NSSLQTSDST VPASVVIQPI
SGLSLQPTVT SANLTIGPLS EQDSVLTTNS SGTQDLTQVM TSQGLVSPSG GPHEITLTIN
NSSLSQVLAQ AAGPTATSSS GSPQEITLTI SELNTTSGSL PSTTPMSPSA ISTQNLVMSS
SGVGGDASVT LTLADTQGML SGGLDTVTLN ITSQGQQFPA LLTDPSLSGQ GGAGSPQVIL
VSHTPQSASA ACEEIAYQVA GVSGNLAPGN QPEKEGRAHQ CLECDRAFSS AAVLMHHSKE
VHGRERIHGC PVCRKAFKRA THLKEHMQTH QAGPSLSSQK PRVFKCDTCE KAFAKPSQLE
RHSRIHTGER PFHCTLCEKA FNQKSALQVH MKKHTGERPY KCAYCVMGFT QKSNMKLHMR
RAHSYAGALQ ESAGHPEQDG EELSRTLHLE EVVQEAAGEW QTLTHVF
//
