ID A0A2I2YYL1_GORGO Unreviewed; 1726 AA.
AC A0A2I2YYL1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=PATJ crumbs cell polarity complex component {ECO:0000313|Ensembl:ENSGGOP00000040087.1};
GN Name=PATJ {ECO:0000313|Ensembl:ENSGGOP00000040087.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000040087.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000040087.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000040087.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000040087.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030003560; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003561; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003563; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003566; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030003569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9593.ENSGGOP00000040087; -.
DR Ensembl; ENSGGOT00000058134.1; ENSGGOP00000040087.1; ENSGGOG00000010129.3.
DR GeneTree; ENSGT00940000155136; -.
DR InParanoid; A0A2I2YYL1; -.
DR OMA; RQIEYIN; -.
DR Proteomes; UP000001519; Chromosome 1.
DR Bgee; ENSGGOG00000010129; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0045177; C:apical part of cell; IBA:GO_Central.
DR GO; GO:0005923; C:bicellular tight junction; IBA:GO_Central.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031023; P:microtubule organizing center organization; IBA:GO_Central.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0120192; P:tight junction assembly; IBA:GO_Central.
DR CDD; cd00992; PDZ_signaling; 10.
DR Gene3D; 1.20.1440.360; -; 1.
DR Gene3D; 2.30.42.10; -; 10.
DR InterPro; IPR015132; L27_2.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964:SF11; INAD-LIKE PROTEIN; 1.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR Pfam; PF09045; L27_2; 1.
DR Pfam; PF00595; PDZ; 10.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 10.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 10.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 10.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 5..65
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 134..221
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 248..328
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 365..453
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 553..639
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 686..758
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1069..1132
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1177..1260
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1375..1458
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1471..1553
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1597..1687
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 452..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1127..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1270..1297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1558..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1726 AA; 188252 MW; C685D6D0CD9D1BA6 CRC64;
MPENPATDKL QVLQVLDRLK MKLQEKGDTS QNEKLSMFYE TLKSPLFNQI LTLQQSIKQL
KGQLNHIPSD CSANFDFSRK GLLVFTDGSI TNGNVHRPSN NSTVSGLFPW TPKLGNEDFN
SVIQQMAQGR QIEYIDIERP STGGLGFSVV ALRSQNLGKV DIFVKDVQPG SVADRDQRLK
ENDQILAINH TPLDQNISHQ QAIALLQQTA GSLRLIVARE PVHTKSSTSS SLTDTTLPET
VCWGHVEEVE LINDGSGLGF GIVGGKTSGV VVRTIVPGGL ADRDGRLQTG DHILKIGGTN
VQGMTSEQVA QVLRNCGNSV RMLVARDPAG DISVTPPAPA ALPVALPTVA SKGPGSDSSL
FETYNVELVR KDGQSLGIRI VGYVGTSHTG EASGIYVKSV IPGSAAYHNG HIQVNDKIVA
VDGVNIQGFA NHDVVEVLRN AGQVVHLTLV RRKTSSSTSP LEPPSDRGTV VEPLKPPALF
LTGAVETETN VDGEDEEIKE RMDTLKNDNI QALEKLEKVP DSPENELKSR WENLLGPDYE
VMVATLDTQI ADDAELQKYS KLLPIHTLRL GVEVDSFDGH HYISSIVSGG PVDTLGLLQP
EDELLEVNGM QLYGKSRREA VSFLKEVPPP FTLVCCRRLF DDEASVDEPR RTETSLPVTE
VDHNMDVNTE EDDDGELALW SPEVKIVELV KDCKGLGFSI LDYQDPLDPT RSVIVIRSLV
ADGVAERSGG LLPGDRLVSV NEYCLDNTSL AEAVEILKAV PPGLVHLGIC KPLVEDNKEE
ESCYILHSSS NEDETEFSGT IHDINSSLIL EAPKGFRNEP YFKEELVDEP FLDLGKSFHS
QQKEIEQSKE AWEMHEFLTP RLQEMDEERE MLVDEEYELY QDPSPSMELY PLSHIQEATP
VPSVNELHFG TQWLHDNEPS ESQEARTGRT VYSQEAQPYG YCPENVMKEN FVMESLPSVP
STEGNSQQGR FDDLENLNSL AKTSLDLGMI PNDVQGPSLL IDLPVVAQSR EQEDLPLYQH
QATRVISKAS AYTGMLSSRY ATDTCELPER EEGEGEETPN FSHWGPPRIV EIFREPNVSL
GISIVGGQTV IKRLKNGEEL KGIFIKQVLE DSPAGKTNAL KTGDKILERQ GTAPPPMKLP
PPYKALTDDS DENEEEDAFT DQKIRQRYAD LPGELHIIEL EKDKNGLGLS LAGNKDRSRM
SIFVVGINPE GPAATDGRMH IGDELLEINN QILYGRSHQY ASAIIKTAPS KVKLVFIRNE
DAVNQMAVTP FPVPSSSPSS IEDQSSTEPI SSEEDGSLEV GIKQLPESES FKLAVSQMKQ
QKYPTKVSFS SQEIPLAPAS SYHSTDADFT GYGGFQAPLS VDPATCPIVP GQEMIIEISK
GRSGLGLSIV GGKDTPLNAI VIHEVYEEGA AARDGRLWAG DQILEVNGVD LRNSSHEEAI
TALRQTPQKV RLVVYRDEAH YRDEENLEIF PVDLQKKAGR GLGLSIVGKR NGSGVFISDI
VKGGAADLDG RLIQGDQILS VNGEDMRNAS QETVATILKC AQGLVQLEIG RLRAGSWTSA
RKTSQNSQGS QQSAHSSCHP SFAPVITGLQ NLVGTKRVSD PSQKNSELSD ALGISIAGGR
GSPLGDIPVF IAMIQASGVA ARTQKLKVGD RIVSINGQPL DGLSHADVVN LLKNAYGHII
LQVVADTNIS AIAAQLENMS TGYHLGLPTA EHHPEDTEEQ LQTMAD
//
