ID A0A2I2Z2E2_GORGO Unreviewed; 117 AA.
AC A0A2I2Z2E2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Signal transducer and activator of transcription 4 {ECO:0000313|Ensembl:ENSGGOP00000041337.1};
GN Name=STAT4 {ECO:0000313|Ensembl:ENSGGOP00000041337.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000041337.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000041337.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000041337.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000041337.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030017656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017658; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017660; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017661; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017662; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017663; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017664; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017665; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2Z2E2; -.
DR SMR; A0A2I2Z2E2; -.
DR Ensembl; ENSGGOT00000062752.1; ENSGGOP00000041337.1; ENSGGOG00000042976.1.
DR GeneTree; ENSGT01050000244905; -.
DR Proteomes; UP000001519; Chromosome 2B.
DR Bgee; ENSGGOG00000042976; Expressed in testis and 4 other cell types or tissues.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.532.10; STAT transcription factor, N-terminal domain; 1.
DR InterPro; IPR001217; STAT.
DR InterPro; IPR036535; STAT_N_sf.
DR InterPro; IPR013799; STAT_TF_prot_interaction.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF19; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4; 1.
DR Pfam; PF02865; STAT_int; 1.
DR SMART; SM00964; STAT_int; 1.
DR SUPFAM; SSF48092; Transcription factor STAT-4 N-domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999}.
FT DOMAIN 2..101
FT /note="STAT transcription factor protein interaction"
FT /evidence="ECO:0000259|SMART:SM00964"
SQ SEQUENCE 117 AA; 13710 MW; FEF5559DA655C932 CRC64;
MSQWNQVQQL EIKFLEQVDQ FYDDNFPMEI RHLLAQWIEN QDWEAASNNE TMATILLQNL
LIQLDEQLGR VSKEKNLLLI HNLKRIRKVL QSPGLATAQL PLDRHGETCI QRSKSCP
//
