ID A0A2I2Z8R9_GORGO Unreviewed; 432 AA.
AC A0A2I2Z8R9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger protein interacting with K protein 1 {ECO:0000313|Ensembl:ENSGGOP00000043552.1};
GN Name=ZIK1 {ECO:0000313|Ensembl:ENSGGOP00000043552.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000043552.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000043552.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000043552.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000043552.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CABD030115095; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018871369.1; XM_019015824.1.
DR AlphaFoldDB; A0A2I2Z8R9; -.
DR Ensembl; ENSGGOT00000065555.1; ENSGGOP00000043552.1; ENSGGOG00000041163.1.
DR GeneID; 101153849; -.
DR CTD; 284307; -.
DR GeneTree; ENSGT00940000162907; -.
DR OMA; WDVEKDL; -.
DR OrthoDB; 5261861at2759; -.
DR Proteomes; UP000001519; Chromosome 19.
DR Bgee; ENSGGOG00000041163; Expressed in cerebellum and 5 other cell types or tissues.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 9.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24390; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24390:SF245; ZINC FINGER PROTEIN 383-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 184..211
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 212..239
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 240..267
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 268..295
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 296..323
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 324..351
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 352..379
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 380..407
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 408..432
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 15..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 48575 MW; DBEB71CFFE9102E0 CRC64;
MLENFALVAS LGCGHGTEDE ETPSDQNVSV GVSQSKAGSS TQKTQSCEMC VPVLKDILHL
ADLPGQKPYL VGECTNHHQH QKHHSAKKSL KRDMDRASYV KCCLFCMSLK PFRKWEVGKD
LPAMLGLLRS LVFPGGKKPS TITECGEDIR SQKSHYKSGE CGKASRHKHT PVYHPRVYTG
KKLYECSKCG KAFRGKYSLV QHQRVHTGER PWECNECGKF FSQTSHLNDH RRIHTGERPY
ECSECGKLFR QNSSLVDHQK IHTGARPYEC SQCGKSFSQK ATLVKHQRVH TGERPYKCGE
CGNSFSQSAI LNQHRRIHTG AKPYKCGQCG KSFSQKATLI KHQRVHTGER PYKCGDCGKS
FSQSSILIQH RRIHTGARPY ECGQCGKSFS QKSGLIQHQV VHTGERPYEC NKCGNSFSQC
SSLIHHQKCH NT
//
